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Report #2825373

Received Feb 8, 2025

HospitalizedOffice visit
A note on interpretation. VAERS reports are unverified and may be incomplete or coincidental. A report does not establish that a vaccine caused an event, and counts should not be used to calculate incidence or infer causation. Full disclaimer

Overview

Sex
Female
Age
72 yrs
State
NH
Recovered
Not recovered
Vaccinated
Sep 15, 2023
Onset
Oct 1, 2023
Days to onset
16
Hospital days
9

Vaccines (1)

TypeNameManufacturerDoseLotRoute / Site
VARZOSZOSTER (SHINGRIX)GLAXOSMITHKLINE BIOLOGICALSUNK——

Symptoms (25)

Aldolase normalAnaemia macrocyticBiopsy bone marrow abnormalBiopsy muscle abnormalBlood creatine phosphokinase normalBone marrow failureDysphoniaDysstasiaFasciitisGait disturbanceImmune thrombocytopeniaImmunoglobulin therapyLaboratory test normalLymphocytic infiltrationMagnetic resonance imaging abnormalMastication disorderMobility decreasedMuscle spasmsMuscular weaknessPosture abnormalPruritusSpeech disorderTongue movement disturbanceTrismusWalking aid user

Symptom narrative

In 9/15/23 she got a shingles shot. In October 2023 she has noticed it is hard to hold her head up and she was more hunched over in her walking. 10/5/23 she had flu shot. 10/27/23 she got covid shot. At the beginning of November 2023, she then had difficulty with lifting her arms to reach for things and shampooing her hair. She has also had itchiness in her elbow and waist that is new around March 2024. In 4/2024 Dr started a trial of prednisone 10 mg daily x2 weeks then 5 mg x 2 weeks which led to room spinning dizziness. It was stopped early because of the dizziness. It did not help her muscles. Hot showers make her itchiness worse. In May-June 2024 she began having difficulty with chewing food. She had to break food into small pieces, even a banana. Her dentist noticed that she cannot open her mouth wide. Food can get stuck in pockets in her mouth. In July 2024, climbing stairs has become difficult and she has to use one step at a time. She has difficulty getting in and out of bed. Since July 2024 she started using a walker. Going down the steps is not as hard. Her foot does not catch on the top of stairs. In July 2024 she noticed that her speech changed, such that it is softer. The pronunciation is also somewhat worse. She cannot whistle anymore. She has trouble licking her ice cream cone because her tongue is not able to extend as far anymore. In 8/2024 her hands started cramping up. On examination she had diffuse muscular weakness in the arms, legs, trunk, and neck. She had difficulty standing unassisted. prednisone 60 mg daily without benefit. has received IVIG in early 2/2025. too early to tell if it has led to benefit.

Current illness

none

Medical history

Atrial fibrillation, glaucoma, hypothyroidism, history of pancreatitis

Other medications

Timolol eye drops, levothyroxine , furosemide , estradiol cream, apixaban, diltiazem, flecainide

Allergies

pitted fruit, almonds, dog danger, nectarine, peach: itching, coughing sneezing

Lab data

MRI of the thigh and humerus showed thickened fascia and muscle biopsy showed lymphocytic infiltration of the fascia and mild lymphocytic perivascular infiltrates consistent with fasciitis. strangely, CK and aldolase were normal. Extensive rheumatologic, infectious, and inflammatory investigations were negative. She then later developed presumed autoimmune thrombocytopenia and macrocytic anemia. bone marrow biopsy showed hypocellular bone marrow.