Received Feb 24, 2025
| Type | Name | Manufacturer | Dose | Lot | Route / Site |
|---|---|---|---|---|---|
| HEPAB | HEP A + HEP B (TWINRIX) | GLAXOSMITHKLINE BIOLOGICALS | UNK | — | IM / RA |
swollen lymph nodes; throat itchy; jaw irritation; having swollen lips; throat itchy and painful,; This non-serious case was reported by a consumer via call center representative and described the occurrence of swollen lymph nodes in a 65-year-old male patient who received HAB (Twinrix) for prophylaxis. Co-suspect products included Typhoid vaccine for prophylaxis. On 07-FEB-2025, the patient received Twinrix (intramuscular, right arm). On 05-FEB-2025, the patient received Typhoid vaccine (left arm). On 10-FEB-2025, 3 days after receiving Twinrix, the patient experienced swollen lymph nodes (Verbatim: swollen lymph nodes), itchy throat (Verbatim: throat itchy), mouth irritation (Verbatim: jaw irritation), lip swelling (Verbatim: having swollen lips) and sore throat (Verbatim: throat itchy and painful,). The outcome of the swollen lymph nodes, itchy throat, mouth irritation, lip swelling and sore throat were not resolved. It was unknown if the reporter considered the swollen lymph nodes, itchy throat, mouth irritation, lip swelling and sore throat to be related to Twinrix and Twinrix Pre-Filled Syringe Device. It was unknown if the company considered the swollen lymph nodes, itchy throat, mouth irritation, lip swelling and sore throat to be related to Twinrix and Twinrix Pre-Filled Syringe Device. This report is made by GSK without prejudice and does not imply any admission or liability for the incident or its consequences. Additional Information: GSK receipt Date: 12-FEB-2025 The patient was the reporter who received the Twinrix vaccine on and started having symptoms. The reporter stated he also received the Typhoid vaccine. The reporter stated that after the Twinrix vaccine, he noticed within 48 hours that he had swollen lips, swollen lymph nodes, jaw irritation, and his throat was itchy and painful. All these symptoms were ongoing. The reporter stated he was going to see his health case professional on the day of reporting. The reporter consented to follow-up. The Vaccine Administration Facility was the same as the Primary Reporter.