Received Apr 17, 2025
| Type | Name | Manufacturer | Dose | Lot | Route / Site |
|---|---|---|---|---|---|
| COVID19 | COVID19 (COVID19 (MODERNA)) | MODERNA | 1 | 039A21A | — |
The first vaccine made my symptoms 30% better. I definitely felt 30% better; I had long COVID for an entire year before I got the vaccine/previous symptoms came rushing back/I progressively got worse and worse to where my pain; This spontaneous case was reported by a patient and describes the occurrence of POST-ACUTE COVID-19 SYNDROME (I had long COVID for an entire year before I got the vaccine/previous symptoms came rushing back/I progressively got worse and worse to where my pain) and THERAPEUTIC RESPONSE UNEXPECTED (The first vaccine made my symptoms 30% better. I definitely felt 30% better) in a 56-year-old male patient who received mRNA-1273 (Moderna COVID-19 Vaccine) (batch nos. 045B21A and 039A21A) for COVID-19 prophylaxis. Concurrent medical conditions included Long COVID (Patient caught COVID on 16-Mar-2020. Patient did get the Moderna vaccine but had long COVID for an entire year before got the vaccine. At the time of reporting, long COVID symptoms were mild comparatively) since 16-Mar-2020. On 02-Apr-2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 01-May-2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular use) dosage was changed to 1 dosage form. In 2021, the patient experienced POST-ACUTE COVID-19 SYNDROME (I had long COVID for an entire year before I got the vaccine/previous symptoms came rushing back/I progressively got worse and worse to where my pain). On an unknown date, the patient experienced THERAPEUTIC RESPONSE UNEXPECTED (The first vaccine made my symptoms 30% better. I definitely felt 30% better). At the time of the report, POST-ACUTE COVID-19 SYNDROME (I had long COVID for an entire year before I got the vaccine/previous symptoms came rushing back/I progressively got worse and worse to where my pain) had not resolved and THERAPEUTIC RESPONSE UNEXPECTED (The first vaccine made my symptoms 30% better. I definitely felt 30% better) outcome was unknown. For mRNA-1273 (Moderna COVID-19 Vaccine) (Unknown), the reporter did not provide any causality assessments. No concomitant medication was reported. No other vaccines were given to the patient within the 4 weeks. At the time of reporting, patient's long COVID symptoms were mild comparatively. To what happened to him after he got the vaccine and just to be specific, the first vaccine made his symptoms 30 percent better and definitely felt 30 percent better. Patient got the first vaccine and woke up 24 hours later, his symptoms were 30 percent better. After getting the second vaccine, within 24 hours all those previous symptoms came rushing back and over the course of the next couple of months, he progressively got worse and worse to where his pain and the new symptoms that he acquired. Patient was so debilitating like it progressively led to him having to stop working. Patient went on disability and had been treating this ever since. The first day patient felt symptoms was on 16-Mar-2020. Patient was an athlete, he ran up, up to like between 5 and 10 miles a week, depending on how much time he had. Patient swam a few miles every week. Patient was very extremely active and physical; he hadn't been the same ever since. There was evidence that it was viral persistence. Patient was living with his 81-year-old mother. It was unknown if the patient experienced any additional symptoms or events. Reporter causality was not reported. No treatment information was provided.; Reporter's Comments: Company comment: The benefit-risk relationship of product is not affected by this report.
Long COVID (Patient caught COVID on 16-Mar-2020. Patient did get the Moderna vaccine but had long COVID for an entire year before got the vaccine. At the time of reporting, long COVID symptoms were mild comparatively)