Received May 13, 2025
| Type | Name | Manufacturer | Dose | Lot | Route / Site |
|---|---|---|---|---|---|
| VARZOS | ZOSTER (SHINGRIX) | GLAXOSMITHKLINE BIOLOGICALS | 1 | UNK | LA |
shingles in her eye; Blindness/ went blind in eye/woke up to shadows, like a curtain over her eye; eye is itchy; This serious case was reported by a consumer via call center representative and described the occurrence of ophthalmic herpes zoster in a 55-year-old female patient who received Herpes zoster (Shingrix) for prophylaxis. On 09-NOV-2023, the patient received the 1st dose of Shingrix (left arm). In NOV-2023, less than a month after receiving Shingrix, the patient experienced ophthalmic herpes zoster (Verbatim: shingles in her eye) (serious criteria GSK medically significant) and blindness (Verbatim: Blindness/ went blind in eye/woke up to shadows, like a curtain over her eye) (serious criteria GSK medically significant). On an unknown date, the patient experienced eye pruritus (Verbatim: eye is itchy). The patient was treated with valaciclovir (Valacyclovir). In NOV-2023, the outcome of the ophthalmic herpes zoster and blindness were resolved. The outcome of the eye pruritus was not resolved. It was unknown if the reporter considered the ophthalmic herpes zoster, blindness and eye pruritus to be related to Shingrix. The company considered the ophthalmic herpes zoster, blindness and eye pruritus to be unrelated to Shingrix. Additional Information: GSK Receipt Date: 05-MAY-2025 and 06-MAY-2025 The reporter reported that she woke up to shadows, like a curtain over her eye, blind in her eye (unknown eye) around 18-November-2023. The patient reported that she had shingles in her eye (unknown eye). The patient reported that blindness lasted for a good week (no specific date provided). The patient did see an Ophthalmologist, and received prescriptions from her pharmacy on 19-November-2023 for several eye drops (unknown products information), and Valacyclovir 500mg, 1 Tablet three times a day (might be) for 10 days, quantity 30. The patient also reported that she never received the second dose of Shingrix because what she experienced after the first dose was scary. The patient also reports that her eye was itchy at the time of reporting, and she thought she had shingles in her eye again. The patient reported received vaccination for shingles. The patient went blind in eye now the repercussions were could get shingles at any time for the rest of life. The patient was 53 and company does not even take responsibility for that and why did not even pay the eye doctor bills that's ridiculous.; Sender's Comments: Ophthalmic herpes zoster, Blindness and Eye pruritus are unlisted events which are considered unrelated to GSK vaccine Shingrix.