Received May 28, 2025
| Type | Name | Manufacturer | Dose | Lot | Route / Site |
|---|---|---|---|---|---|
| COVID19 | COVID19 (COVID19 (MODERNA)) | MODERNA | UNK | — | IM |
experienced ongoing pain, fatigue, and weakness; experienced ongoing pain, fatigue, and weakness; experienced ongoing pain, fatigue, and weakness; This spontaneous case was reported by a patient and describes the occurrence of ASTHENIA (experienced ongoing pain, fatigue, and weakness), PAIN (experienced ongoing pain, fatigue, and weakness) and FATIGUE (experienced ongoing pain, fatigue, and weakness) in a 73-year-old female patient who received mRNA-1273.712 (SPIKEVAX 2024-2025 PFS) for COVID-19 prophylaxis. Previously administered products included for COVID-19 prophylaxis: Moderna COVID-19 vaccine; for Product used for unknown indication: Pfizer vaccine and Pfizer vaccine. Past adverse reactions to the above products included Fatigue with Pfizer vaccine; Feeling unwell with Pfizer vaccine; and No adverse effect with Moderna COVID-19 vaccine. On 21-May-2025, the patient received dose of mRNA-1273.712 (SPIKEVAX 2024-2025 PFS) (Intramuscular use) 1 dosage form. In May 2025, the patient experienced ASTHENIA (experienced ongoing pain, fatigue, and weakness), PAIN (experienced ongoing pain, fatigue, and weakness) and FATIGUE (experienced ongoing pain, fatigue, and weakness). At the time of the report, ASTHENIA (experienced ongoing pain, fatigue, and weakness), PAIN (experienced ongoing pain, fatigue, and weakness) and FATIGUE (experienced ongoing pain, fatigue, and weakness) had not resolved. No concomitant medication was reported. The patient started getting COVID-19 vaccinations in early 2021. At first, chose Pfizer and stuck with it, even though it usually made unwell for about half a day and often needing to leave work early due to fatigue. Later, during a busy holiday period, she received a Moderna shot by accident because forgot to ask which brand was being administered. To their surprise, she had no side effects at all with Moderna. Since then, she chose to continue with Moderna, as it seemed to work better for them. Most recently, she received the 2024/2025 Moderna vaccine late on a 21-May-2025 evening, around 6 PM. She experienced ongoing pain, fatigue, and weakness and much stronger symptoms than any she had with Moderna before. She was asking what the difference was between the 2023 and the new 2024/2025 Moderna vaccines. She was concerned because she never had this kind of reaction to Moderna before. It was unknown if the patient experienced any additional symptoms or events. Reporter causality was not reported. No treatment medication was reported. Reporter did not allow further contact