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Report #2843588

Received Jun 2, 2025

A note on interpretation. VAERS reports are unverified and may be incomplete or coincidental. A report does not establish that a vaccine caused an event, and counts should not be used to calculate incidence or infer causation. Full disclaimer

Overview

Sex
Female
Age
47 yrs
State
MA
Recovered
Not recovered
Vaccinated
May 31, 2025
Onset
Jun 1, 2025
Days to onset
1
Hospital days
—

Vaccines (1)

TypeNameManufacturerDoseLotRoute / Site
PNC21PNEUMO (CAPVAXIVE)MERCK & CO. INC.1—SYR / LA

Symptoms (10)

ChillsFatigueInfluenza like illnessInjection site erythemaLymphadenopathyMyalgiaPain in extremityPyrexiaThroat irritationUpper-airway cough syndrome

Symptom narrative

I received the CAPVAXIVE (21-valent pneumococcal conjugate) vaccine on Saturday, May 31st around 3:00 PM at a pharmacy. The vaccine was administered as part of an immunological workup due to suspected immune dysfunction (possible CVID or MCAS), to evaluate my ability to mount an appropriate antibody response. Within 24 hours, I developed significant arm pain and redness at the injection site, which progressively worsened rather than improved. By 36?48 hours post-injection, the pain had intensified and spread from the deltoid area down into the lower bicep, with visible redness and swelling. I also experienced chills, deep fatigue, and flu-like symptoms, leading me to go to bed at 4:45 PM the following day. As of today (just under 48 hours post-vaccine), I continue to have significant fatigue, a low-grade fever, mild throat irritation, postnasal drip, and swollen lymph nodes? all localized to the left side only, corresponding with the arm where the vaccine was administered. The red area on my arm is about the size of a palm. For symptom management, I?ve used Zyrtec (cetirizine), famotidine, as well as Advil (ibuprofen) every 4?6 hours. This combination makes it possible to lift my arm, but the pain returns between doses. I plan to go to bed early again due to ongoing fatigue. No formal medical evaluation yet. Symptoms are still active at the time of this report.

Current illness

None

Medical history

Unknown autoimmune problem (doctor using vaccine as a challenge)

Other medications

Propranolol, Metformin, Hydrochlorothiazide, Dextroamphetamine, Spironolactone, armour thyroid, famotidine, Zyrtec

Allergies

Azithromycin, sulfa

Lab data

n/a