Received Jul 9, 2025
| Type | Name | Manufacturer | Dose | Lot | Route / Site |
|---|---|---|---|---|---|
| HEPAB | HEP A + HEP B (TWINRIX) | GLAXOSMITHKLINE BIOLOGICALS | 3 | — | — |
| HEPAB | HEP A + HEP B (TWINRIX) | GLAXOSMITHKLINE BIOLOGICALS | 2 | — | — |
received 3rd dose on 13-MAY-2014; Early 2nd dose; This non-serious case was reported by a pharmacist via call center representative and described the occurrence of drug dose administration interval too long in a 65-year-old female patient who received HAB (Twinrix) for prophylaxis. Co-suspect products included HAB (Twinrix) for prophylaxis. Concomitant products included HEPATITIS A VACCINE INACT;HEPATITIS B VACCINE RHBSAG (YEAST) (TWINRIX). On 13-MAY-2014, the patient received the 3rd dose of Twinrix. On 22-NOV-2013, the patient received the 2nd dose of Twinrix. On 22-NOV-2013, not applicable after receiving Twinrix and an unknown time after receiving Twinrix, the patient experienced drug dose administration interval too short (Verbatim: Early 2nd dose). On 13-MAY-2014, the patient experienced drug dose administration interval too long (Verbatim: received 3rd dose on 13-MAY-2014). The outcome of the drug dose administration interval too long and drug dose administration interval too short were not applicable. This report is made by GSK without prejudice and does not imply any admission or liability for the incident or its consequences. Additional Information: GSK Receipt Date: 27-JUN-2025 The pharmacist called to request information about the possibility of getting Hepatitis B titers to make sure she was covered. The patient received 1st dose of Twinrix on 10-NOV-2013, 2nd dose on 22-NOV-2013 and 3rd dose on 13-MAY-2014 The reporter did not know if those dates were accurate and would get in contact with physician to confirm the dates. The patient was the health care professional and has 65 year of age at the moment. The patient received 2nd dose of Twinrix vaccine earlier than recommended interval, which led to shortening of vaccination schedule. The patient received 3rd dose of Twinrix, later than the recommended interval, which led to lengthening of vaccination schedule.
TWINRIX