Received Jul 10, 2025
| Type | Name | Manufacturer | Dose | Lot | Route / Site |
|---|---|---|---|---|---|
| MMR | MEASLES + MUMPS + RUBELLA (PRIORIX) | GLAXOSMITHKLINE BIOLOGICALS | UNK | UNK | — |
titer test showed zero immunity again; This non-serious case was reported by a consumer via call center representative and described the occurrence of therapy non-responder in a female patient who received MMR (Priorix) for prophylaxis. Previously administered products included MMR vaccine (received in 1963) and MMR (received in 1983). Concurrent medical conditions included mast cell activation syndrome (Consumer states she has mast cell activation syndrome and is injected with IgE. Consumer states her last vaccination with IgE was 15 APR 2025). Concomitant products included Measles vaccine, Mumps vaccine, Rubella vaccine (Mmr). On 25-APR-2025, the patient received Priorix. On an unknown date, an unknown time after receiving Priorix, the patient experienced therapy non-responder (Verbatim: titer test showed zero immunity again). The outcome of the therapy non-responder was not applicable. This report is made by GSK without prejudice and does not imply any admission or liability for the incident or its consequences. Additional Information: GSK receipt Date: 20-JUN-2025 Consumer states she has mast cell activation syndrome and is injected with IgE. Consumer states her last vaccination with IgE was 15 APR 2025 The reporter states that she was vaccinated with an MMR vaccine in 1963 and in 1983 (unknown name and specific dates.) Consumer states she had a titer test for MMR and the results noted zero immunity. The consumer states she was vaccinated again with an MMR vaccine on 27 APR 2025 and titer test showed zero immunity again (lack of effect.) Consumer could not provide the lot number for the vaccine, however, she was able to provide an national drug code number. The national drug code number she provided was for an MMR vaccine manufactured by MERCK SHARP and DOHME. Consumer was unable to verify having received an MMR vaccine manufactured by GSK, however, she states she thought she did receive an MMR vaccine manufactured by GSK. Consumer will follow up with safety to cancel case or call GSK to cancel case if she finds she did not receive MMR vaccine manufactured by GSK. Consumer states she has a lot going on and she may have gotten confused after having had an endoscopy (date not disclosed) and medication associated with that procedure. Consumer also states she will be a participant in a clinical trial for an antiviral (undisclosed diagnosis) starting soon. No further information was provided/obtained. Its not indicated for adults. Consumer calls back to cancel this report. She received an MMR vaccine manufactured by another pharmaceutical company (MSD.)
Mast cell activation syndrome (Consumer states she has mast cell activation syndrome and is injected with IgE. Consumer states her last vaccination with IgE was 15 APR 2025)
Comments: List of non-encoded Patient Relevant History: Patient Other Relevant History 1: Mmr
MMR