Received Jul 28, 2025
| Type | Name | Manufacturer | Dose | Lot | Route / Site |
|---|---|---|---|---|---|
| HEP | HEP B (HEPLISAV-B) | DYNAVAX TECHNOLOGIES CORPORATION | 1 | 946065 | IM |
Our Patient Received Twinrix As A Second Dose After Receiving A First Dose of Heplisav-B; Initial report received on 15-Jul-2025. A pharmacist reported that a 31-year-old male patient (race and ethnicity not reported) received HEPLISAV-B (hepatitis B vaccine) for hepatitis B immunization and then received TWINRIX as a second dose. No medical history or concomitant medications were reported. In Jun-2025, the patient received dose 1 of a hepatitis B vaccine [HEPLISAV-B (lot # 946065, expiration date 02-Nov-2027, NDC # 43528-0003-05, route and site not available). On an unknown date, after having been vaccinated with HEPLISAV-B, the patient received a dose of TWINRIX (no details provided) as a second dose of hepatitis B vaccination. The reporter stated that the patient had no other side effects reported. No other information was available. Company Comment: The company assessed the event as non-serious.; Sender's Comments: The company assessed the event as non-serious.