Received Aug 5, 2025
| Type | Name | Manufacturer | Dose | Lot | Route / Site |
|---|---|---|---|---|---|
| FLUX | INFLUENZA (SEASONAL) (NO BRAND NAME) | UNKNOWN MANUFACTURER | UNK | UNK | — |
| VARZOS | ZOSTER (SHINGRIX) | GLAXOSMITHKLINE BIOLOGICALS | UNK | UNK | — |
Angry Red Shoulder; This non-serious case was reported by a pharmacist via sales rep and described the occurrence of localized erythema in an unspecified number of patients who received Herpes zoster (Shingrix) for prophylaxis. Co-suspect products included Flu unspecified (Flu vaccine) for prophylaxis. On an unknown date, the patients received Shingrix (unknown arm) and Flu vaccine. On an unknown date, an unknown time after receiving Shingrix and Flu vaccine, the patients experienced localized erythema (Verbatim: Angry Red Shoulder). The outcome of the localized erythema was resolved. The reporter considered the localized erythema to be related to Shingrix. It was unknown if the reporter considered the localized erythema to be related to Flu vaccine. The company considered the localized erythema to be related to Shingrix. It was unknown if the company considered the localized erythema to be related to Flu vaccine. Additional Information: GSK Receipt Date: 18-JUL-2025 A Population Health Pharmacist at a top 200 healthcare system wanted to know if certain patients had a genetic predisposition to experience more severe local reactions with Shingrix. She shared that some patients experienced an angry red shoulder, while others could barely tell where the vaccination had been given. She had seen the same thing when patients received an adjuvanted flu vaccine. When asked about the age of the patients in whom she had noticed this difference more often, she shared that it was usually not the elderly, but patients in their 40s and 50s.