Received Aug 7, 2025
| Type | Name | Manufacturer | Dose | Lot | Route / Site |
|---|---|---|---|---|---|
| PNC20 | PNEUMO (PREVNAR20) | PFIZER\WYETH | 1 | LN4930 | LA |
Swelling; Inflammation to the upper arm spreading through the lower arm; extreme redness to upper arm spreading to lower arm - feels warm to touch, itchy and tight; extreme redness to upper arm spreading to lower arm - feels warm to touch, itchy and tight/Hot to touch; arm pain; extreme redness to upper arm spreading to lower arm - feels warm to touch, itchy and tight/Redness; extreme redness to upper arm spreading to lower arm - feels warm to touch, itchy and tight/Itchiness; fever of 101 (tympanic); chills; This is a spontaneous report received from a Nurse. A 50-year-old female patient (unknown if pregnant) received pneumococcal 20-val conj vac (dipht CRM197 protein) (PREVNAR 20), on 25Jul2025 as dose 1, single (Lot number: LN4930, Expiration Date: 31Jul2026) at the age of 50 years, in left arm for immunisation, Device Lot Number: LN4930, Device Expiration Date: 31Jul2026. The patient's relevant medical history and concomitant medications were not reported. The following information was reported: PAIN IN EXTREMITY (non-serious) with onset 26Jul2025, outcome "recovering", described as "arm pain"; CHILLS (non-serious) with onset 26Jul2025, outcome "recovering"; SKIN TIGHTNESS (non-serious) with onset 26Jul2025, outcome "recovering", described as "extreme redness to upper arm spreading to lower arm - feels warm to touch, itchy and tight"; FEELING HOT (non-serious) with onset 26Jul2025, outcome "recovering", described as "extreme redness to upper arm spreading to lower arm - feels warm to touch, itchy and tight/Hot to touch"; PRURITUS (non-serious) with onset 26Jul2025, outcome "recovering", described as "extreme redness to upper arm spreading to lower arm - feels warm to touch, itchy and tight/Itchiness"; ERYTHEMA (non-serious) with onset 26Jul2025, outcome "recovering", described as "extreme redness to upper arm spreading to lower arm - feels warm to touch, itchy and tight/Redness"; PYREXIA (non-serious) with onset 26Jul2025, outcome "recovering", described as "fever of 101 (tympanic)"; INFLAMMATION (non-serious), outcome "unknown", described as "Inflammation to the upper arm spreading through the lower arm"; SWELLING (non-serious), outcome "unknown". Therapeutic measures were taken as a result of feeling hot, skin tightness, pain in extremity, erythema, pruritus, pyrexia, chills. Additional information: The patient receive any other vaccines on the same date as the vaccine(s) reported as no. The patient receive any other vaccines within 4 weeks PRIOR to the vaccine(s) reported as no. The patient taking any other medications within 2 weeks of the event starting reported as unknown. The treatment received for the adverse event; Orders placed to shut down inflammation process - Doxycycline, Prednisone, Triamcinolone, Zyrtec. This is the first case out of Two split cases. Concern: Reporter stated, " just reporting some adverse reaction to the Prevnar 20 Vaccine for two, two of our patients." When paraphrased the above concern: Reporter stated, "Yes. There's two of the patients received the Prevnar 20 and it's within the same LOT number." When probed to clarify if reporter need any medical enquiry: Reporter stated, "Not medical enquiry, just like we are already treating, the primary care is already treating the patient. So, I just want to know what we are supposed to do.