Received Sep 1, 2025
| Type | Name | Manufacturer | Dose | Lot | Route / Site |
|---|---|---|---|---|---|
| UNK | VACCINE NOT SPECIFIED (NO BRAND NAME) | UNKNOWN MANUFACTURER | UNK | — | — |
| MMR | MEASLES + MUMPS + RUBELLA (MMR II) | MERCK & CO. INC. | 1 | — | — |
| RVX | ROTAVIRUS (NO BRAND NAME) | UNKNOWN MANUFACTURER | UNK | — | — |
drug-vaccine interaction; This spontaneous report was received from another health professional via other company and refers to a 73-year-old female patient. The patient's medical history and concomitant therapies were not reported. As concurrent conditions were reported hip injury, lupus, and rheumatoid arthritis. On an unknown date, the patient started therapy with Dupilumab (DUPIXENT) 300 mg, QOW, administered by Subcutaneous route (lot # and expiration date were not reported) for other chronic obstructive pulmonary disease. On 09-Jul-2025, the patient was vaccinated with a dose of Measles, Mumps, and Rubella (Wistar RA 27-3) Virus Vaccine, Live (manufacturer unknown), dose number 1, 0.5 mL (0.5 mL / Two dose series), (lot # and expiration date were not reported) diluted with a with sterile diluent (manufacturer unknown), (expiration date, and lot # were not reported); additional the patient also was vaccinated with a dose of Respiratory syncytial virus vaccine (RSV vaccine) (lot # and expiration date were not reported), both vaccines administered as prophylaxis (also reported as "Measles, Mumps, Rubella vaccination"). On the same date (09-Jul-2025), the patient experienced a Vaccine-drug interaction, following the first dose intake of Dupilumab (DUPIXENT) and following administration of Measles, Mumps, and Rubella (Wistar RA 27-3) Virus Vaccine, Live (manufacturer unknown) and Respiratory syncytial virus vaccine (RSV vaccine) (same date latency). The outcome of the Vaccine-drug interaction was unknown. The action taken with Dupixent (Dupilumab) was reported as unknown. The causality assessment between the Vaccine-drug interaction and the administration of Dupilumab (DUPIXENT), Measles, Mumps, and Rubella (Wistar RA 27-3) Virus Vaccine, Live (manufacturer unknown), sterile diluent (manufacturer unknown) and Respiratory syncytial virus vaccine (RSV vaccine) was considered as related.
Hip injury; Lupus syndrome; Rheumatoid arthritis
STERILE DILUENT; DUPIXENT