Received Aug 11, 2025
| Type | Name | Manufacturer | Dose | Lot | Route / Site |
|---|---|---|---|---|---|
| VARZOS | ZOSTER (SHINGRIX) | GLAXOSMITHKLINE BIOLOGICALS | UNK | UNK | — |
suspected vaccination failure; I have had this twice, I still feel the effects from second time; This serious case was reported by a consumer and described the occurrence of vaccination failure in a patient who received Herpes zoster (Shingrix) for prophylaxis. Concurrent medical conditions included malignant lymphoma. On an unknown date, the patient received Shingrix. On an unknown date, an unknown time after receiving Shingrix, the patient experienced vaccination failure (Verbatim: suspected vaccination failure) (serious criteria GSK medically significant) and shingles (Verbatim: I have had this shit twice, I still feel the effects from second time). The outcome of the vaccination failure was not reported and the outcome of the shingles was not resolved. It was unknown if the reporter considered the vaccination failure and shingles to be related to Shingrix. The company considered the vaccination failure to be unrelated to Shingrix. It was unknown if the company considered the shingles to be related to Shingrix. Additional Information: GSK receipt date: 02-AUG-2025 The patient reported that his/her oncologist had recommended that he/she receive the shingles vaccine because he/she had cancer lymphoma. He/she had already experienced shingles twice and was still feeling the effects from the second time. The patient went to local pharmacy where they quoted dollar 210 for the vaccine. Just one mile down the road quoted dollar 263 for the same vaccine over dollar 50 more. He/she had Medicare and previously had prescription coverage, but he/she was told he/she no longer qualified because his/her monthly social security disability income was dollar 1,841, which was apparently too high. The patient was frustrated and angry about how pharmacies could charge so much for a necessary vaccine, and how prices could vary so drastically between locations so close to each other. He/she considered sending this issue to office to see what they thought, because he/she believed someone should be held accountable. This case was considered as suspected vaccination failure since the details regarding completion of primary vaccine schedule, time to onset and laboratory confirmation of shingles were unknown at the time of reporting.; Sender's Comments: Vaccination failure is a listed event which, due to the following criteria (insufficient information provided about the clinical description, details regarding completion of primary vaccination schedule, time to onset and laboratory confirmation of disease) is considered unrelated to GSK vaccine Shingrix.
Malignant lymphoma