Report #2854767

Overview

Sex

Male

Age

Age unknown

State

MD

Recovered

Unknown

Vaccinated

—

Onset

—

Days to onset

—

Hospital days

—

Symptoms (1)

Symptom narrative

suboptimal pneumococcal titers despite vaccination; This literature marketed report has been received from the authors of a published article, and refers to a 9-year-old male patient. The patient's medical history included platelet transfusions, hypercellular marrow with megakaryocytic hypoplasia, recurrent pneumonias, prenatal intrauterine grown restriction, postnatal small size for gestational age, and congenital microcephaly. The patient's concurrent conditions included chromosomal microarray, Fanconi's anaemia, significant B-cell and mild T-cell lymphopenia, normocytic anemia, thrombocytopenia, and undetectable levels of IgA. Concomitant therapies were not reported. On an unknown date, the patient was vaccinated with Pneumococcal 15-valent Conjugate Vaccine (VAXNEUVANCE); or Pneumococcal 21-valent Conjugate Vaccine (CAPVAXIVE); or Pneumococcal Vaccine, Polyvalent (23-valent) (PNEUMOVAX 23) (formulation, lor #, expiration date, exact dose, route of administration and anatomical location were not provided) for prophylaxis. On an unknown date, the patient experienced antibody test abnormal (reported as: suboptimal pneumococcal titers despite vaccination). At the reporting time, the outcome of antibody test abnormal was unknown. The reporter considered the event of antibody test abnormal to be related to Pneumococcal 15-valent Conjugate Vaccine (VAXNEUVANCE); or Pneumococcal 21-valent Conjugate Vaccine (CAPVAXIVE); or Pneumococcal Vaccine, Polyvalent (23-valent) (PNEUMOVAX 23).

Current illness

Chromosome abnormality; Fanconi's anaemia; Immunoglobulin A low; Lymphopenia; Normocytic anemia; Thrombocytopenia

Medical history

Medical History/Concurrent Conditions: Foetal growth restriction; Marrow hypercellular; Microcephaly; Platelet transfusion; Pneumonia recurrent; Small for gestational age