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Report #2856498

Received Sep 2, 2025

ER / ED visitOffice visit
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Overview

Sex
Male
Age
41 yrs
State
FL
Recovered
Not recovered
Vaccinated
Jun 5, 2025
Onset
Jun 5, 2025
Days to onset
0
Hospital days
—

Vaccines (1)

TypeNameManufacturerDoseLotRoute / Site
SMALLMNKSMALLPOX + MONKEYPOX (JYNNEOS)BAVARIAN NORDIC196868SC / RA

Symptoms (11)

Antinuclear antibody negativeC-reactive protein normalChlamydia test positiveEar pruritusHIV antibody negativeInflammationInjection site swellingPapulePruritusSwellingSyphilis test negative

Symptom narrative

Patient reports had R arm swelling after the vaccination that started at vaccination area and progressed entire R arm and to chest over a few days. As was in a travel clinic consultation also received a MCV4- Meningococcal vaccination and Typhoid vaccination the same day/time however on the LEFT DELTOID, both IM. MENINGOCOCCAL MCV4O Date Administered: Jun 05, 2025 13:00 Series: Booster Manufacturer: GLAXOSMITHKLINE Lot: 9X7CD Exp Date: Jan 31, 2026 NDC: 058160082730 Admin Route/Site: INTRAMUSCULAR/LEFT DELTOID Dosage: 0.5mL ++++++++++++++++++++++++++ Administered: TYPHOID, VICPS Date Administered: Jun 05, 2025 13:00 Series: Complete Manufacturer: SANOFI PASTEUR Lot: Y2A021M Exp Date: Mar 31, 2027 NDC: 049281079051 Admin Route/Site: INTRAMUSCULAR/LEFT DELTOID Dosage: 0.5mL Vaccine Information Statement(s): TYPHOID VIS Oct 30, 2019

Current illness

none known

Medical history

Chronic rhinitis, work related PTSD, obstructive sleep apnea (on autopap at night)

Other medications

Had been on one month duration of Truvada daily, fluoxetine 60mg/day, trazadone, omeprazole, sildenafil, biotin, magnesium oxide, vitamin a, zinc gluconate, flaxseed

Allergies

Tamazepam (rash), soy (urticaria)

Lab data

Patient went to ER multiple times and noted had some relief with a steroid injection but no relief with oral steroids. Relief with clobetasol cream but not triamcinolone cream. Saw both allergy and dermatology and multiple times infectious disease services for follow-up. Lab tests returned HIV Ab/Ag neg on 5/5/25, 7/17/25, and 7/31/25. Trep IgG neg 7/17/25 and 7/31/25. Negative ANA screening and CRP on 8/26/26, as we were concerned that patient may have have an underlying, previously undiagnosed immune disorder. Also taking multiple vitamins that had not affected condition previously. Allergy consultation stated that would be very unusual to have such a prolonged vaccination reaction and advised supportive care, as did dermatology but also treated with ivermectin (did not help). Examination in person revealed flat papules in genital area (likely c/w HPV new per patient since vaccination) that were not migratory and very fine follicular inflammation thought to be immune reaction / folliculitis, As of 9/2/25, continues to have migratory pruritis (ears, arms). Even though positive for urinary chlamydia on 7/17/25, this was not though to be contributing to current symptoms that started nearly one month earlier 6/5/25.