Received Sep 5, 2025
| Type | Name | Manufacturer | Dose | Lot | Route / Site |
|---|---|---|---|---|---|
| COVID19 | COVID19 (COVID19 (MODERNA)) | MODERNA | 1 | — | — |
Indolent lymphoma/started progressing in Summer of 2024; This spontaneous case was reported by a consumer and describes the occurrence of MALIGNANT NEOPLASM PROGRESSION (Indolent lymphoma/started progressing in Summer of 2024) in a 71-year-old female patient who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 prophylaxis. The patient's past medical history included Kidney cancer and Renal surgery (Kidney cancer treated surgically). Concurrent medical conditions included Lymphoma (Indolent lymphoma) since 2020. In January 2021, the patient received first dose of mRNA-1273 (Moderna COVID-19 Vaccine) (Intramuscular use) 1 dosage form. In 2021, received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. In August 2021, received third dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. In 2024, the patient experienced MALIGNANT NEOPLASM PROGRESSION (Indolent lymphoma/started progressing in Summer of 2024) (seriousness criterion medically significant). At the time of the report, MALIGNANT NEOPLASM PROGRESSION (Indolent lymphoma/started progressing in Summer of 2024) was resolving. Concomitant medication use information was not provided by reporter. In 2020, the patient was diagnosed with indolent lymphoma, and the physicians took the decision to watch and wait. It started progressing in the summer of 2024, and the treatment started in December and finished chemotherapy in April 2025. It was unknown if the patient experienced any additional symptoms/events.; Reporter's Comments: Past medical history of Kidney cancer, concurrent medical condition Lymphoma are contributors for the event. Due to lack of biological plausibility, the causality of the event was assessed as not related to the vaccine. The benefit -risk relationship of product is not affected by this report.
Lymphoma (Indolent lymphoma)
Medical History/Concurrent Conditions: Kidney cancer; Renal surgery (Kidney cancer treated surgically)