Received Sep 19, 2025
| Type | Name | Manufacturer | Dose | Lot | Route / Site |
|---|---|---|---|---|---|
| COVID19 | COVID19 (COVID19 (MODERNA)) | MODERNA | UNK | — | — |
Pars planitis; retinal tears; Partial empty sella suggesting idiopathic intracranial hypertension; venous sheathing; Progressive vision changes with episodes of gray cast; Electric shocks/zaps in the feet; limb weakness and limp; stuttering and speech/swallowing difficulties; stuttering and speech/swallowing difficulties; cognitive difficulties; episodes of extreme fatigue and excessive sleepiness; Widespread body pain; arthritis-like joint pain; Intermittent loss of bladder control; generalized malaise; episodes of extreme fatigue and excessive sleepiness; Nausea; fevers; This spontaneous case was reported by a consumer and describes the occurrence of UVEITIS (Pars planitis), RETINAL TEAR (retinal tears), IDIOPATHIC INTRACRANIAL HYPERTENSION (Partial empty sella suggesting idiopathic intracranial hypertension) and RETINAL VASCULITIS (venous sheathing) in a patient of an unknown age and gender who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 prophylaxis. The occurrence of additional non-serious events is detailed below. No Medical History information was reported. On 17-Aug-2021, the patient received dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On 01-Oct-2021, received dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) dosage was changed to 1 dosage form. On an unknown date, the patient experienced UVEITIS (Pars planitis) (seriousness criterion medically significant), RETINAL TEAR (retinal tears) (seriousness criterion medically significant), IDIOPATHIC INTRACRANIAL HYPERTENSION (Partial empty sella suggesting idiopathic intracranial hypertension) (seriousness criterion medically significant), RETINAL VASCULITIS (venous sheathing) (seriousness criterion medically significant), VISUAL IMPAIRMENT (Progressive vision changes with episodes of gray cast), NEURALGIA (Electric shocks/zaps in the feet), MUSCULAR WEAKNESS (limb weakness and limp), DYSPHEMIA (stuttering and speech/swallowing difficulties), DYSPHAGIA (stuttering and speech/swallowing difficulties), COGNITIVE DISORDER (cognitive difficulties), HYPERSOMNIA (episodes of extreme fatigue and excessive sleepiness), PAIN (Widespread body pain), ARTHRITIS (arthritis-like joint pain), URINARY INCONTINENCE (Intermittent loss of bladder control), MALAISE (generalized malaise), FATIGUE (episodes of extreme fatigue and excessive sleepiness), NAUSEA (Nausea) and PYREXIA (fevers). At the time of the report, UVEITIS (Pars planitis), RETINAL TEAR (retinal tears), IDIOPATHIC INTRACRANIAL HYPERTENSION (Partial empty sella suggesting idiopathic intracranial hypertension), RETINAL VASCULITIS (venous sheathing), VISUAL IMPAIRMENT (Progressive vision changes with episodes of gray cast), NEURALGIA (Electric shocks/zaps in the feet), MUSCULAR WEAKNESS (limb weakness and limp), DYSPHEMIA (stuttering and speech/swallowing difficulties), DYSPHAGIA (stuttering and speech/swallowing difficulties), COGNITIVE DISORDER (cognitive difficulties), HYPERSOMNIA (episodes of extreme fatigue and excessive sleepiness), PAIN (Widespread body pain), ARTHRITIS (arthritis-like joint pain), URINARY INCONTINENCE (Intermittent loss of bladder control), MALAISE (generalized malaise), FATIGUE (episodes of extreme fatigue and excessive sleepiness), NAUSEA (Nausea) and PYREXIA (fevers) outcome was unknown. DIAGNOSTIC RESULTS (normal ranges are provided in parenthesis if available): On an unknown date, Antinuclear antibody: Fluctuating. On an unknown date, Antiphospholipid antibodies: antiphospholipid and Lyme antibody reactivity (band 41 which is non specific to Lyme) despite no known exposure. On an unknown date, Autoantibody test: presence of both cytoplasmic and nuclear autoantibodies. On an unknown date, Magnetic resonance imaging: Showed nonspecific punctate white matter foci, possible spinal cord lesions, tapered stenosis of distal transverse sinuses bilaterally, and a partial empty sella suggesting idiopathic intracranial hypertension. No concomitant medications were reported. The patient planned lumbar puncture to rule out MS and/or the possible intracranial hypertension (which has been deemed idiopathic). It was possible that the vaccine triggered adverse reactions and provoked an uproar within my immune system, genuinely believe that it activated something, unmasking or accelerating an underlying vulnerability that may had already existed. The patient fully understood the difference between causation and correlation and took into account. However, considering the broader picture and the fact that the patient had no prior autoimmune markers or symptoms before this vaccination. It was difficult not to associate the patient current health issues with it. No treatment medications were reported.; Reporter's Comments: The benefit -risk relationship of product is not affected by this report.
Test Name: ANA (Antinuclear Antibody); Result Unstructured Data: Fluctuating; Test Name: Antiphospholipid Antibodies; Result Unstructured Data: antiphospholipid and Lyme antibody reactivity (band 41 which is non specific to Lyme) despite no known exposure,; Test Name: Autoantibodies; Result Unstructured Data: presence of both cytoplasmic and nuclear autoantibodies; Test Name: MRI; Result Unstructured Data: Showed nonspecific punctate white matter foci, possible spinal cord lesions, tapered stenosis of distal transverse sinuses bilaterally, and a partial empty sella suggesting idiopathic intracranial hypertension