Received Sep 22, 2025
| Type | Name | Manufacturer | Dose | Lot | Route / Site |
|---|---|---|---|---|---|
| UNK | VACCINE NOT SPECIFIED (NO BRAND NAME) | UNKNOWN MANUFACTURER | UNK | — | IM |
lethargic; started to feel a little bit of arthritis in his hands which he always has but was getting worse; getting a low-grade headache (annoying); more body aches in my other joints - knees and shoulders; 'fuzzy' feeling in my head not concentrating or alert as normal; Tired; Doesn´t want to do nothing; This spontaneous case was reported by a consumer and describes the occurrence of DISTURBANCE IN ATTENTION ('fuzzy' feeling in my head not concentrating or alert as normal), LETHARGY (lethargic), ARTHRITIS (started to feel a little bit of arthritis in his hands which he always has but was getting worse), DECREASED ACTIVITY (Doesn´t want to do nothing) and HEADACHE (getting a low-grade headache (annoying)) in a 71-year-old male patient who received mRNA-1283 (MNEXSPIKE PFS) for COVID-19 prophylaxis. The occurrence of additional non-serious events is detailed below. Concurrent medical conditions included Hand arthritis. On 10-Sep-2025, the patient received dose of mRNA-1283 (MNEXSPIKE PFS) (Intramuscular use) .2 milliliter. On 11-Sep-2025, the patient experienced DISTURBANCE IN ATTENTION ('fuzzy' feeling in my head not concentrating or alert as normal), ARTHRITIS (started to feel a little bit of arthritis in his hands which he always has but was getting worse), HEADACHE (getting a low-grade headache (annoying)) and ARTHRALGIA (more body aches in my other joints - knees and shoulders). On 12-Sep-2025, the patient experienced LETHARGY (lethargic). In September 2025, the patient experienced DECREASED ACTIVITY (Doesn´t want to do nothing) and FATIGUE (Tired). On 12-Sep-2025, HEADACHE (getting a low-grade headache (annoying)) and ARTHRALGIA (more body aches in my other joints - knees and shoulders) had resolved. At the time of the report, DISTURBANCE IN ATTENTION ('fuzzy' feeling in my head not concentrating or alert as normal), DECREASED ACTIVITY (Doesn´t want to do nothing) and FATIGUE (Tired) outcome was unknown and LETHARGY (lethargic) and ARTHRITIS (started to feel a little bit of arthritis in his hands which he always has but was getting worse) had not resolved. No concomitant medications were reported. The patient received vaccine on 10-Sep-2025 around 5 o'clock in the evening. It made him sick for a day, he was fine on the 10th, no problems until the middle of the day on 11-Sep-2025, he started to get a 'fuzzy' feeling in my head not concentrating or alert as normal. Then he started to feel a little bit of arthritis in his hands, which he always had but was getting worse and later in the day around 4 or 5 o'clock more body aches in his other joints - knees and shoulders. He never got a real strong headache, but his head was tired and did not feel sharp (was not sharp and alert). He got a low-grade headache (annoying) and did not have a temperature. Skipped class too and went to bed early. In Friday morning, he was still achy in hands and joints, and now just kind of tired and did not want to do anything but no fever, no headache and pretty much all the joint pain was gone. It was unknown if the patient experienced any additional symptoms/events. No treatment information was provided. This case was linked to US-MODERNATX, INC.-MOD-2025-789410 (E2B Linked Report).; Reporter's Comments: The benefit-risk relationship of product is not affected by this report.; Sender's Comments: US-MODERNATX, INC.-MOD-2025-789410:Wife case
Hand arthritis