Received Nov 4, 2025
| Type | Name | Manufacturer | Dose | Lot | Route / Site |
|---|---|---|---|---|---|
| VARZOS | ZOSTER (NO BRAND NAME) | UNKNOWN MANUFACTURER | UNK | UNK | — |
Suspected vaccination failure; My husband has been taking the shingles shot since kidney failure and transplant. This year he got shingles; This serious case was reported by a consumer via interactive digital media and described the occurrence of vaccination failure in a adult male patient who received Herpes zoster (Shingles vaccine) for prophylaxis. The patient's past medical history included renal failure and kidney transplant. On an unknown date, the patient received Shingles vaccine. On an unknown date, an unknown time after receiving Shingles vaccine, the patient experienced vaccination failure (Verbatim: Suspected vaccination failure) (serious criteria GSK medically significant) and shingles (Verbatim: My husband has been taking the shingles shot since kidney failure and transplant. This year he got shingles). The outcome of the vaccination failure was not reported, and the outcome of the shingles was not resolved. The reporter considered the vaccination failure and shingles to be related to Shingles vaccine. The company considered the vaccination failure and shingles to be unrelated to Shingles vaccine. Additional Information: GSK Receipt Date: 23-OCT-2025 This case was reported by a patient's wife via interactive digital media. The reporter's husband had been taking the shingles shot since kidney failure and transplant. This year he got shingles. This case was considered as suspected vaccination failure since the details regarding the completion of primary vaccination schedule, time to onset and laboratory confirmation of shingles were unknown at the time of reporting. This case has been linked with case US2025AMR139264, reported by the same reporter for different patient. The batch number was not provided, and we are unable to contact the reporter.; Sender's Comments: A case of Vaccination failure and Herpes zoster, on an unknown time after receiving Shingles vaccine, in a male patient. Based on the available information a possible causality that the events were caused by GSK vaccine product cannot be ascertained. Consent for further follow up has not been received US-GSK-US2025AMR139264:same reporter different patient
Medical History/Concurrent Conditions: Kidney transplant; Renal failure