Received Nov 5, 2025
| Type | Name | Manufacturer | Dose | Lot | Route / Site |
|---|---|---|---|---|---|
| VARZOS | ZOSTER (NO BRAND NAME) | UNKNOWN MANUFACTURER | 2 | UNK | — |
| VARZOS | ZOSTER (NO BRAND NAME) | UNKNOWN MANUFACTURER | 1 | UNK | — |
Suspected vaccination failure; shingles on left leg/painful/blisters; weak; can hardly walk; This serious case was reported by a consumer via interactive digital media and described the occurrence of vaccination failure in a patient who received Herpes zoster (Shingles vaccine) for prophylaxis. Co-suspect products included Herpes zoster (Shingles vaccine) for prophylaxis. The patient's past medical history included chickenpox (had chicken pox as a kid). Concurrent medical conditions included multiple sclerosis. On an unknown date, the patient received the 2nd dose of Shingles vaccine and the 1st dose of Shingles vaccine. On an unknown date, an unknown time after receiving Shingles vaccine and Shingles vaccine, the patient experienced vaccination failure (Verbatim: Suspected vaccination failure) (serious criteria GSK medically significant), shingles (Verbatim: shingles on left leg/painful/blisters), weakness (Verbatim: weak) and walking difficulty (Verbatim: can hardly walk). The patient was treated with gabapentin (Gabapentine) and Antivirals. The outcome of the vaccination failure was not reported and the outcome of the shingles, weakness and walking difficulty were not resolved. It was unknown if the reporter considered the vaccination failure, shingles, weakness and walking difficulty to be related to Shingles vaccine and Shingles vaccine. The company considered the vaccination failure to be unrelated to Shingles vaccine and Shingles vaccine. It was unknown if the company considered the shingles, weakness and walking difficulty to be related to Shingles vaccine and Shingles vaccine. Additional Information: GSK Receipt Date: 25-OCT-2025 This case was reported by a patient via interactive digital media. Patient had Shingles and stated it was painful, he or she had it on left leg. According to physician it was unusual, patient was on anti-viral and Gabapentin which was helping. Patient was so weak that he/she could hardly walk on the day of reporting blisters showed up. Patient's left thigh was sore, and he/she was using the Nerve Cream there. The batch number was not provided, and we are unable to contact the reporter. This case was considered as suspected vaccination failure as details time to onset for shingles and laboratory confirmation regarding shingles were unknown at the time of reporting.; Sender's Comments: A case of Vaccination failure, an unknown time after receiving 2nd dose of Shingles, in a patient. Based on the available information a possible causality that the event was caused by GSK vaccine product cannot be ascertained. Consent for further follow up has not been received
Multiple sclerosis
Medical History/Concurrent Conditions: Chickenpox (had chicken pox as a kid)