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Report #2872220

Received Nov 12, 2025

A note on interpretation. VAERS reports are unverified and may be incomplete or coincidental. A report does not establish that a vaccine caused an event, and counts should not be used to calculate incidence or infer causation. Full disclaimer

Overview

Sex
Female
Age
Age unknown
State
ME
Recovered
Unknown
Vaccinated
—
Onset
—
Days to onset
—
Hospital days
—

Vaccines (1)

TypeNameManufacturerDoseLotRoute / Site
COVID19COVID19 (COVID19 (MODERNA))MODERNAUNK——

Symptoms (2)

PruritusUrticaria

Symptom narrative

Pruritis with long-term cetirizine use. I started using OTC cetirizine in 2021 when I moved to a new area and was experiencing fall allergies that I'd never had before. I had used it for childhood allergies and used it prn as an adult. I continue to use it about half of the time because it makes me drowsy, so if I was working a long shift the next day I would skip it the night before. I started to noticed that if I hadn't taken it for 2-3 days in a row, I would get hives very easily and be itchy all over. That would go away shortly after taking another one. I believe it was 2022 when I started to notice this, maybe early 2023. I still take 5-10mg of cetirizine almost every night, because I will start to get hives / itchiness 24-48 hours after taking it. I've tried cutting down to 5mg recently but the effects seem to wear off a little earlier. I told my doctor about this in June but I don't think he reported it, he suggested maybe switching to another antihistamine which I will try. Also, there were case studies a few years ago about patients who received Moderna having pruritis that goes away with cetirizine. I did not have a moderna vaccine until 2022, so the timing would be right. I am not sure if these two things are connected, but I think it's interesting that this is a drug that has been around for a long time and only now people are reporting this side effect. I'm a pharmacist and not anti-vax. I even got moderna again this year, to be clear. But I have a feeling this could be connected. I have used brand Zyrtec, store off-brand and store off-brand, I am not certain which I was using when I started to notice the issue.

Medical history

Asthma, hypothyroidism

Other medications

levothyroxine 25mcg; Liquid iron, liquid multivitamin, cetirizine

Allergies

Cats, dustmites