Received Nov 17, 2025
| Type | Name | Manufacturer | Dose | Lot | Route / Site |
|---|---|---|---|---|---|
| VARZOS | ZOSTER (NO BRAND NAME) | UNKNOWN MANUFACTURER | 2 | UNK | — |
| VARZOS | ZOSTER (NO BRAND NAME) | UNKNOWN MANUFACTURER | 1 | UNK | — |
they got activated when you got your surgery/ suspected vaccination failure; Hip replacement; they got activated when you got your surgery; This serious case was reported by a consumer via interactive digital media and described the occurrence of vaccination failure in a patient who received Herpes zoster (Shingles vaccine) for prophylaxis. Co-suspect products included Herpes zoster (Shingles vaccine) for prophylaxis. On an unknown date, the patient received the 2nd dose of Shingles vaccine and the 1st dose of Shingles vaccine. On an unknown date, an unknown time after receiving Shingles vaccine and Shingles vaccine, the patient experienced vaccination failure (Verbatim: they got activated when you got your surgery/ suspected vaccination failure) (serious criteria GSK medically significant), hip replacement (Verbatim: Hip replacement) (serious criteria clinically significant/intervention required) and shingles (Verbatim: they got activated when you got your surgery). The outcome of the vaccination failure, hip replacement and shingles were not reported. It was unknown if the reporter considered the vaccination failure, hip replacement and shingles to be related to Shingles vaccine. It was unknown if the reporter considered the vaccination failure and shingles to be related to Shingles vaccine. The company considered the vaccination failure and hip replacement to be unrelated to Shingles vaccine and Shingles vaccine. It was unknown if the company considered the shingles to be related to Shingles vaccine and Shingles vaccine. Additional Information: GSK Receipt Date: 11-NOV-2025 This case was reported by a patient via interactive digital media. The patient got both vaccine 3 years ago and when he/she had a hip replacement a year and a half, he/she had them but his/her doctor said that they got activated when he/she got surgery. Patient reported that it was the worse and was under a treatment for 14 days. The follow-up could not be possible as no contact details were available. This case was considered as suspected vaccination failure as details regarding time to onset and laboratory test confirming shingles were unknown at the time of reporting. The batch number was not provided, and we are unable to contact the reporter.; Sender's Comments: A case of Vaccination failure and Hip arthroplasty, unknown time after receiving Shingles vaccine( 1st and 2nd ), in a patient. Based on the available information a? possible causality that the event was caused by the GSK product cannot be ascertained. Consent for further follow-up has not been received.