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Report #2873475

Received Nov 18, 2025

ER / ED visitOffice visit
A note on interpretation. VAERS reports are unverified and may be incomplete or coincidental. A report does not establish that a vaccine caused an event, and counts should not be used to calculate incidence or infer causation. Full disclaimer

Overview

Sex
Female
Age
4 yrs
State
FL
Recovered
Recovered
Vaccinated
Oct 20, 2025
Onset
Oct 21, 2025
Days to onset
1
Hospital days
—

Vaccines (1)

TypeNameManufacturerDoseLotRoute / Site
DTAPIPVDTAP + IPV (QUADRACEL)SANOFI PASTEURUNKU8198AAIM / RL

Symptoms (10)

Injection site discolourationInjection site erythemaInjection site indurationInjection site massInjection site painInjection site pruritusInjection site scarInjection site swellingInjection site vesiclesInjection site warmth

Symptom narrative

Around 24 hrs post-vaccination, patient had a red, warm, swollen area at the site of injection on her right thigh. Initially it appeared to be a normal injection site side effect, but throughout the course of the day it continued to enlarge. At the end of that day, approx. 36 hrs after injection, the site had swelled and a hard lump could be felt deep in the leg. The redness spread to approx. 4 inches in diameter across the patients thigh. Patient complained of itchiness and pain, and small vesicles/blisters were noted at the center of the site. No fever or other systemic reaction was noted. The blisters continued to worsen over the next 12 hours, becoming quite large and the redness also appeared to have a bullseye or "ring" appearance that was progressing outward, as in the outer edges of the site were the most warm/red. At this point (48 hrs post-vaccination) the patient was seen in her primary care doctors office and a course of antibiotics (Keflex) were prescribed. They also advised to administer an antihistamine and topical corticosteroids. The following day, the site had not worsened but seemed to be fluctuating between appearing to improve, then the redness/bullseye appearance worsening and patient complaining of intense pain and itching. Patient was advised by primary care to be taken to the ER to rule out an infection or abscess, but by the time patient had reached the ER the site was improving again. Over the next 24 hours the injection site continued to fluctuate in appearance, sometimes looking red and causing intense itching but gradually did improve with no complications. At the time of this report, 1 month post-vaccination, there is still a dark slightly discolored area 4 inches in diameter where the redness had been, and a slight scar from the blistering.

Current illness

Ear Infection

Medical history

Uncombable Hair Syndrome (genetic mutation, does not cause any known medical issues besides frizzy hair)

Other medications

Daily Multivitamin + Iron

Allergies

None

Lab data

N/A