Received Nov 19, 2025
| Type | Name | Manufacturer | Dose | Lot | Route / Site |
|---|---|---|---|---|---|
| COVID19 | COVID19 (COVID19 (MODERNA MNEXSPIKE)) | MODERNA | UNK | — | IM |
severe constipation; caller was in pain until he went to the bathroom; This spontaneous case was reported by a consumer and describes the occurrence of CONSTIPATION (severe constipation) and DYSCHEZIA (caller was in pain until he went to the bathroom) in an 85-year-old male patient who received mRNA-1273.251 (Spikevax LP.8.1 PFS) for COVID-19 prophylaxis. The suspect product included Pre-filled Syringe injection for COVID-19 prophylaxis. Previously administered products included for Product used for unknown indication: INFLUENZA VACCINE in October 2025. Past adverse reactions to the above products included No adverse effect with INFLUENZA VACCINE. Concurrent medical conditions included Osteoporosis. On 12-Nov-2025, the patient received dose of mRNA-1273.251 (Spikevax LP.8.1 PFS) (Intramuscular use) .5 milliliter. On an unknown date, the patient started Pre-filled Syringe (unknown route) at an unspecified dose. On 13-Nov-2025, the patient experienced CONSTIPATION (severe constipation) and DYSCHEZIA (caller was in pain until he went to the bathroom). On 13-Nov-2025, CONSTIPATION (severe constipation) and DYSCHEZIA (caller was in pain until he went to the bathroom) had resolved. The action taken with mRNA-1273.251 (Spikevax LP.8.1 PFS) (Intramuscular use) was unknown. Concomitant medications were not reported. It was reported that 3 weeks before patient took flu shot. It was reported that the patient was experiencing severe constipation approximately 12 hours after receiving the vaccine, describing it as the most painful constipation ever. Patient mentioned that he had never experienced constipation before. After about 5 hours, patient was able to go to the bathroom and empty his bowels. The caller was in pain until he went to the bathroom and unsure about what was happening. It was unknown if the patient experienced any additional symptoms/events. Treatment information was not reported.
Osteoporosis