Received Nov 21, 2025
| Type | Name | Manufacturer | Dose | Lot | Route / Site |
|---|---|---|---|---|---|
| VARZOS | ZOSTER (SHINGRIX) | GLAXOSMITHKLINE BIOLOGICALS | 1 | 23E4B | IM / RA |
Approximately 17 hours after vaccine, patient experienced numbness/tingling in upper and lower extremities. Due to symptoms and family history of Guillain-Barre syndrome, admitted for GBS work-up labs and MRI attempt 11/11/25. Unable to tolerate duration of MRI. 11/12/25 no progression of paresthesias. 11/13/25 patient reported improvement of symptoms. 11/14/25 MRI of brain and spine with and without contrast and Lumbar puncture. 11/15/25 Discharged-patient reported symptoms almost completely resolved. Patient to follow-up with PCP, neurology and rheumatology.
Patient states she has been healthy
Heterozygous factor V Leiden mutation, Hypothyroidism, Autonomic neuropathy associated with Type1 diabetes mellitus, Morbid Obesity, Mixed hyperlipidemia, Bipolar 1 Disorder, Other Depression, Anxiety, Essential Tremor, Nocturnal Hypoxia, Hypertension, Acute saddle pulmonary embolism without acute cor pumonale, Esophageal dysmotility, Autoimmune hepatitis, Pityriasis Rosea, Rheumatoid arteritis, Rheumatoid arthritis of multiple sites with negative rheumatoid factor, Osteoarthritis of knees-bilateral, Facet arthropathy-lumbar, Neuropathic pain, Avascular necrosis of bone of right hip, Chronic renal impraiment-stage 3b, Hypoxia, Bilateral lower extremity edema, Polydipsia, Supplemental oxygen dependent
Lamotrigine, Xarelto, Spironolactone, Potassium Chloride ER, Hydromorphone, Ursodiol, Invega Sustenna, Protonix, Pepcid, Multi Complete/Iron, Voltaren 1% Gel, Vitamin D3, Humalog (Insulin Lispro), Calcium Citrate 950, Pepto-Bismol, Azathiop
Sulfa antibiotics, Fluoxetine, Quetiapine, Zinc, Remeron
Labs-thiamine, folate, B12, TSH, RPR and HIV labs. HIV and syphilis were negative and other labs mentioned did not explain symptoms. 11/11/25 unable to tolerate duration of MRI. MRI showed no acute intracranial or spinal abnormalities and no evidence of demyelinating process. Lumbar puncture showed normal proteins and not consistent with GBS. Per discussion with Neurology, could not rule out GBS with MRI and Lumbar puncture-need to discuss with patient IVIG treatment. 11/15/25 results of studies and outpatient IVIG treatment discussed with patient.