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Report #2874966

Received Nov 25, 2025

A note on interpretation. VAERS reports are unverified and may be incomplete or coincidental. A report does not establish that a vaccine caused an event, and counts should not be used to calculate incidence or infer causation. Full disclaimer

Overview

Sex
Male
Age
Age unknown
State
NC
Recovered
Not recovered
Vaccinated
—
Onset
—
Days to onset
—
Hospital days
—

Vaccines (1)

TypeNameManufacturerDoseLotRoute / Site
COVID19COVID19 (COVID19 (MODERNA))MODERNA2——

Symptoms (2)

AstheniaFatigue

Symptom narrative

Severe and persistent fatigue and lack of energy following their second Covid vaccine; Lack of energy following their second Covid vaccine; This spontaneous case was reported by a consumer and describes the occurrence of FATIGUE (Severe and persistent fatigue and lack of energy following their second Covid vaccine) in a male patient of an unknown age who received mRNA-1273 (Moderna COVID-19 Vaccine) for COVID-19 prophylaxis. The occurrence of additional non-serious events is detailed below. No Medical History information was reported. In 2021, the patient received second dose of mRNA-1273 (Moderna COVID-19 Vaccine) (unknown route) 1 dosage form. On an unknown date, the patient experienced FATIGUE (Severe and persistent fatigue and lack of energy following their second Covid vaccine) (seriousness criterion medically significant) and ASTHENIA (Lack of energy following their second Covid vaccine). At the time of the report, FATIGUE (Severe and persistent fatigue and lack of energy following their second Covid vaccine) and ASTHENIA (Lack of energy following their second Covid vaccine) had not resolved. Relevant medical history details of vaccines within the past 4 weeks, medical conditions were not provided. Concomitant medication was not provided. Patient reported severe and persistent fatigue with lack of energy following the second Covid vaccine in Spring 2021, which had significantly impacted his quality of life. He was in bed for two weeks after the vaccine with zero energy and 99 percent fatigue. For the last four and half years it had been fatigue 90 percent of the time and no energy 95 percent of the time. Patient stated that vaccine had screwed up his life. Despite consulting over 20 physicians, patient had not received any helpful insights. He felt that his life had deteriorated since the vaccination and was seeking any potential guidance or support. He expressed frustration with the lack of acknowledgment from healthcare providers and hopes Moderna might have information that could help address his symptoms. It was unknown if the patient experienced any additional symptoms or events. Treatment information was not reported. Most recent FOLLOW-UP information incorporated above includes: On 19-Nov-2025: Non-significant follow up received and updated narrative, references.; Reporter's Comments: The benefit-risk relationship of product is not affected by this report.