Received Dec 15, 2025
| Type | Name | Manufacturer | Dose | Lot | Route / Site |
|---|---|---|---|---|---|
| PPV | PNEUMO (PNEUMOVAX) | MERCK & CO. INC. | UNK | — | — |
| PPV | PNEUMO (NO BRAND NAME) | UNKNOWN MANUFACTURER | UNK | — | — |
suboptimal response to vaccinations against pathogens like Streptococcus pneumoniae; This Literature (Spontaneous) report has been received from the authors of a published article; referred to a 64 -year-old female patient. The patient's concurrent condition included Waldenström's macroglobulinemia. The patient's concomitant medications were not reported. On an unknown date (also reported as 18-year-ago), the patient was vaccinated with PCV13 and PPSV23 for Prophylaxis (strengths, doses, routes of administration, anatomical locations, lots numbers, and expirations dates were not reported). It was reported that the patient visited the emergency room and contrast-enhanced CT scan showed a 5x5 cm ring-enhancing lesion in the subclavicular space, and cultures grew Streptococcus pneumoniae. The authors considered the patient experienced suboptimal response to vaccinations against pathogens like Streptococcus pneumoniae (Vaccination failure) since abscess formation in vaccinated Waldenström's macroglobulinemia patients highlights impaired antibody response (considered Related).
Waldenstrom's macroglobulinemia
Test Name: CT scan; Result Unstructured Data: 5x5 cm ring-enhancing lesion in the subclavicular space; Test Name: cultures; Result Unstructured Data: Streptococcus pneumoniae