Received Jan 9, 2026
| Type | Name | Manufacturer | Dose | Lot | Route / Site |
|---|---|---|---|---|---|
| COVID19 | COVID19 (COVID19 (MODERNA MNEXSPIKE)) | MODERNA | UNK | — | IM |
I have severe arthritis. Nobody with severe arthritis should be given this shot. It weakened my legs.; This spontaneous case was reported by a consumer and describes the occurrence of ARTHRITIS (I have severe arthritis. Nobody with severe arthritis should be given this shot. It weakened my legs.) in an 86-year-old female patient who received mRNA-1273.251 (Spikevax LP.8.1 PFS) for COVID-19 prophylaxis. The suspect product included Pre-filled Syringe injection for COVID-19 prophylaxis. Previously administered products included for COVID-19 prophylaxis: Moderna COVID-19 Vaccine. Past adverse reactions to the above products included No adverse effect with Moderna COVID-19 Vaccine. Concurrent medical conditions included Arthritis (severe). In December 2025, the patient received dose of mRNA-1273.251 (Spikevax LP.8.1 PFS) (Intramuscular use) 1 dosage form. On an unknown date, the patient started Pre-filled Syringe (unknown route) at an unspecified dose. In December 2025, the patient experienced ARTHRITIS (I have severe arthritis. Nobody with severe arthritis should be given this shot. It weakened my legs.). At the time of the report, ARTHRITIS (I have severe arthritis. Nobody with severe arthritis should be given this shot. It weakened my legs.) was resolving. The concomitant medication was not reported by the reporter. It had been 2.5 weeks, and the patient had just begun to get over it. She had severe arthritis. Nobody with severe arthritis should have been given this shot. It weakened her legs. She could not get out of the toilet. She had to call the EMTs to come and get her out of the toilet. It was terrible. She got it from a local pharmacy. The first one she had was a Moderna shot when they first came out, around 2019 or so. She had no problems whatsoever with that one. This one caused her nothing but problems. The effects of this were quite severe. She thought other people needed to be aware of that. It could not provide the name of the Moderna Covid-19 vaccine. It reported getting the shot prior to Christmas but was unable to give a precise date in Dec-2025. It was unknown if the patient experienced any additional symptoms or events. The treatment medication was not reported by the reporter.; Reporter's Comments: Patient's medical history of arthritis as well as advanced age were assessed as confounding factors for reported events. The benefit-risk relationship of the mRNA-1273 is not affected by this report.
Arthritis (severe)