Received Jan 16, 2026
| Type | Name | Manufacturer | Dose | Lot | Route / Site |
|---|---|---|---|---|---|
| VARZOS | ZOSTER (SHINGRIX) | GLAXOSMITHKLINE BIOLOGICALS | 2 | UNK | — |
inflammation completely up our spines, and around and into our brains; Severe, recurrent inflammation up the spine; This serious case was reported by a consumer via interactive digital media and described the occurrence of brain inflammation in a female patient who received Herpes zoster (Shingrix) for prophylaxis. Previously administered products included Shingrix (first dose was received on an unknown date). In OCT-2025, the patient received the 2nd dose of Shingrix. On an unknown date, less than 3 months after receiving Shingrix, the patient experienced brain inflammation (Verbatim: inflammation completely up our spines, and around and into our brains) (serious criteria GSK medically significant) and osteitis (Verbatim: Severe, recurrent inflammation up the spine). The outcome of the brain inflammation and osteitis were not resolved. The reporter considered the brain inflammation and osteitis to be related to Shingrix. The company considered the brain inflammation to be unrelated to Shingrix. The company considered the osteitis to be related to Shingrix. Additional Information: GSK Receipt Date: 10-JAN-2026 This case was reported by a patient via interactive digital media. The patient's husband reported that he and his wife both had the Shingrix vaccine, followed by the booster, 3 months ago. They were suffering with severe recurrent inflammation completely up our spines, and around and into our brains at the time of reporting. The patient was in the worst part of her inflammation which seemed to have lasted for a couple of months. They both agree and know it was a side effect from the shingles vaccine that they took. The patient said that shit was poison, they were still dealing from the effects. The patient said if there was any attorney reading this who could help them please contact them because he had been to three doctors now and none of them know what the issue was. The batch number was not provided, and we are unable to contact the reporter. The case had been linked to US2026AMR003618, reported by the same reporter, for a different patient.; Sender's Comments: A case of Noninfective encephalitis, less than 3 months after receiving the 2nd dose of Shingrix, in a female patient. Based on the available information a?possible causality that the event was caused by the GSK product cannot be ascertained. Consent for further follow-up has not been received. US-GSK-US2026AMR003618:case for Husband