Received Jan 19, 2026
| Type | Name | Manufacturer | Dose | Lot | Route / Site |
|---|---|---|---|---|---|
| VARZOS | ZOSTER (SHINGRIX) | GLAXOSMITHKLINE BIOLOGICALS | UNK | UNK | — |
Suspected Vaccination failure; shingles; This serious case was reported by a consumer via interactive digital media and described the occurrence of vaccination failure in a patient who received Herpes zoster (Shingrix) for prophylaxis. The patient's past medical history included chickenpox. In SEP-2018, the patient received Shingrix. On an unknown date, 7 years after receiving Shingrix, the patient experienced vaccination failure (Verbatim: Suspected Vaccination failure) (serious criteria GSK medically significant) and shingles (Verbatim: shingles). The outcome of the vaccination failure and shingles were not reported. It was unknown if the reporter considered the vaccination failure and shingles to be related to Shingrix. The company considered the vaccination failure to be unrelated to Shingrix. It was unknown if the company considered the shingles to be related to Shingrix. Additional Information: GSK receipt date 13-JAN-2026 This case was reported by a patient via interactive digital media. The patient reported never having had chickenpox but had cared for four children who did, which the patient believed was the likely source of exposure to the virus. A former primary care physician had recommended receiving the shingles vaccine, administered in two doses one month apart. The patient stated that this physician had indicated the vaccine lasted about ten years, but the patient later learned it typically lasted around seven years, with five years considered a safe interval. Patient suggested that the vaccine's effect lasted approximately seven years. The patient planned to receive the next shingles vaccine between the time of reporting and June, with the intention of repeating the vaccination every five years. The patient emphasized a strong dislike for shingles, describing the condition as excruciating. This case was considered as suspected vaccination failure as details regarding confirmation of vaccination schedule and laboratory confirmation regarding shingles were unknown at the time of reporting. The batch number was not provided, and we are unable to contact the reporter.; Sender's Comments: A case of Vaccination failure, 7 years after receiving Shingrix, in a patient. Based on the available information a? possible causality that the event was caused by the GSK product cannot be ascertained. Consent for further follow-up has not been received.
Medical History/Concurrent Conditions: Chickenpox