Received Feb 2, 2026
| Type | Name | Manufacturer | Dose | Lot | Route / Site |
|---|---|---|---|---|---|
| COVID19 | COVID19 (COVID19 (MODERNA MNEXSPIKE)) | MODERNA | UNK | — | IM |
arthritis symptoms have flared notably; RLS type symptoms; This spontaneous case was reported by a consumer and describes the occurrence of ARTHRITIS (arthritis symptoms have flared notably) and RESTLESS LEGS SYNDROME (RLS type symptoms) in a female patient of an unknown age who received mRNA-1273.251 (Spikevax LP.8.1 PFS) for COVID-19 prophylaxis. The suspect product included Pre-filled Syringe injection for COVID-19 prophylaxis. Previously administered products included for Drug use for unknown indication: PFIZER BIONTECH COVID-19 VACCINE. Past adverse reactions to the above products included No adverse effect with PFIZER BIONTECH COVID-19 VACCINE. Concurrent medical conditions included Arthritis (patient also noticed arthritis symptoms had flared notably.). In October 2025, the patient received dose of mRNA-1273.251 (Spikevax LP.8.1 PFS) (Intramuscular use) 1 dosage form. On an unknown date, the patient started Pre-filled Syringe (unknown route) at an unspecified dose. On an unknown date, the patient experienced ARTHRITIS (arthritis symptoms have flared notably) and RESTLESS LEGS SYNDROME (RLS type symptoms). At the time of the report, ARTHRITIS (arthritis symptoms have flared notably) and RESTLESS LEGS SYNDROME (RLS type symptoms) outcome was unknown. Concomitant medication information was not provided. It was reported that the patient had previously received COVID-19 vaccines exclusively from Pfizer until Oct-2025. It was stated that after receiving the Moderna vaccine, she experienced more symptoms than with Pfizer, most notably restless legs syndrome (RLS)-type symptoms. Reporter asked whether this was a known side effect of the Moderna vaccine. And also reported a notable flare-up of her arthritis symptoms and stated that the Moderna vaccine was the only change in her medications over the past few months. It was unknown if the patient experienced any additional symptoms or events. Treatment medication was not reported. This case was linked to MOD-2026-793510, MOD-2026-793510 (Patient Link).; Reporter's Comments: Company Comment: The benefit-risk relationship of the product is not affected by this report.
Arthritis (patient also noticed arthritis symptoms had flared notably.)