Received Feb 9, 2026
| Type | Name | Manufacturer | Dose | Lot | Route / Site |
|---|---|---|---|---|---|
| VARZOS | ZOSTER (NO BRAND NAME) | UNKNOWN MANUFACTURER | UNK | UNK | — |
Suspected vaccination failure; shingles; fever; This serious case was reported by a consumer via interactive digital media and described the occurrence of vaccination failure in a patient who received Herpes zoster (Shingles vaccine) for prophylaxis. The patient's past medical history included shingles and fever. On an unknown date, the patient received Shingles vaccine. On an unknown date, an unknown time after receiving Shingles vaccine, the patient experienced vaccination failure (Verbatim: Suspected vaccination failure) (serious criteria GSK medically significant), shingles (Verbatim: shingles) and fever (Verbatim: fever). The patient was treated with Antivirals. The outcome of the vaccination failure, shingles and fever were not reported. It was unknown if the reporter considered the vaccination failure, shingles and fever to be related to Shingles vaccine. The company considered the vaccination failure to be unrelated to Shingles vaccine. It was unknown if the company considered the shingles and fever to be related to Shingles vaccine. Additional Information: GSK Receipt Date: 03-FEB-2026 The patient reported having experienced shingles three times. The first episode had occurred 55 years earlier, at a time when only pain-relief treatment had been available, which had not helped. The second episode had occurred 20 years earlier and had resolved after treatment with antiviral medication. The patient stated that they had received the shingles vaccines as they became available. The third episode had occurred five years earlier, and antiviral treatment had stopped the symptoms. The patient reported having developed fever blisters every time they ran a fever. The batch number was not provided, and we are unable to contact the reporter. This case was considered as vaccination failure as details regarding confirmation of time to onset for Shingles and laboratory confirmation regarding Shingles were unknown at the time of reporting.; Sender's Comments: A case of Vaccination failure, unknown time after receiving Shingles vaccine, in a patient. Based on the available information a possible causality that the event was caused by the GSK product cannot be ascertained. Consent for further follow-up has not been received.
Medical History/Concurrent Conditions: Fever; Shingles