Received Mar 23, 2026
| Type | Name | Manufacturer | Dose | Lot | Route / Site |
|---|---|---|---|---|---|
| DTAP | DTAP (INFANRIX) | GLAXOSMITHKLINE BIOLOGICALS | 1 | M4ZE7 | IM / RL |
| MMRV | MEASLES + MUMPS + RUBELLA + VARICELLA (PROQUAD) | MERCK & CO. INC. | 1 | Z013988 | IM / RL |
| VARCEL | VARICELLA (VARIVAX) | MERCK & CO. INC. | 1 | Z014869 | IM / LL |
| DTAP | DTAP (INFANRIX) | GLAXOSMITHKLINE BIOLOGICALS | 4 | M4ZET | OT / RL |
| MMRV | MEASLES + MUMPS + RUBELLA + VARICELLA (PROQUAD) | MERCK & CO. INC. | 1 | Z013988 | OT / RL |
| VARCEL | VARICELLA (VARIVAX) | MERCK & CO. INC. | 1 | Z014869 | OT / LL |
what was the patient's response: normal response of irritability/ irritability after administration; inadvertently administered PROQUAD and VARIVAX at the same time; The patient came in for vaccines recommended by the state immunization registry: "DTAP, Varicella and MMR"/I had administered two doses of Varicella by giving Proquad and Varivax; This spontaneous report was received from a medical assistant and refers to a patient of unknown age and gender. The patient's medical history, concurrent conditions, and concomitant therapies were not reported. On 18-Feb-2026, the patient was inadvertently vaccinated with a dose of Measles, Mumps, Rubella and Varicella (Oka-Merck) Virus Vaccine Live (PROQUAD) powder and solvent for solution for injection (lot #Z013988, expiration date: 02-Mar-2027) and Varicella Virus Vaccine Live (Oka-Merck) (VARIVAX) powder and solvent for solution for injection (lot #Z014869, expiration date: 23-Sep-2027) at the same time (Accidental overdose). The vaccines were reconstituted with sterile diluent (Hollister-Stier STERILE DILUENT) solution for injection (indication, expiration date, and lot # were not reported). The patient's family was notified and they were going to continue to monitor the patient. No clinical side effects were noticed at the reporting time. Follow-up has been received from the same reporter (registered medical assistant) on 04-Mar-2026. The patient was an 18-month-old male (also reported as 17-month old, discrepancy). Varicella Virus Vaccine Live (Oka-Merck) (VARIVAX) was administered as first dose by intramuscular route in the left vastus lateralis. Measles, Mumps, Rubella and Varicella (Oka-Merck) Virus Vaccine Live (PROQUAD) was administered as first dose by intramuscular route in the right vastus lateralis. On the same day, the patient was also vaccinated with Infanrix (Diphtheria vaccine toxoid; Pertussis vaccine acellular 3-component;Tetanus vaccine toxoid), fourth dose administered by intramuscular route in the right vastus lateralis. The patient response was irritability after administration. The patient came in for vaccines recommended by the state immunization registry: "DTAP, Varicella and MMR". Other office staff, Certified Nursing Assistant (CNA), obtained vials from refrigerator and asked the reporter to verify the correct immunizations were obtained. While the reporter was in the middle of documenting on a different patient she glanced at vials and stated "yes". When they both entered the room, the mother asked if the reporter could administer the vaccines. Then the patient left the clinic and they were both entering vaccines in registry, they realized that made an error and the reporter administered two doses of Varicella by giving Measles, Mumps, Rubella and Varicella (Oka-Merck) Virus Vaccine Live (PROQUAD) and Varicella Virus Vaccine Live (Oka-Merck) (VARIVAX) to the 17-month-old patient (Wrong product administered). The outcome of the events was unknown. The action taken with the suspect products was not applicable. The causality between the event of irritability after administration and the suspect products was not known.
Sterile diluent