Received Mar 10, 2026
| Type | Name | Manufacturer | Dose | Lot | Route / Site |
|---|---|---|---|---|---|
| VARZOS | ZOSTER (NO BRAND NAME) | UNKNOWN MANUFACTURER | UNK | UNK | — |
Brain surgery; Shingles; suspecetd vaccination failure; This serious case was reported by a consumer via interactive digital media and described the occurrence of vaccination failure in a 59-year-old patient who received Herpes zoster (Shingles vaccine) for prophylaxis. On an unknown date, the patient received Shingles vaccine. On 31-JAN-2026, an unknown time after receiving Shingles vaccine, the patient experienced vaccination failure (Verbatim: suspecetd vaccination failure) (serious criteria GSK medically significant) and shingles (Verbatim: Shingles) (serious criteria disability). On an unknown date, the patient experienced brain operation (Verbatim: Brain surgery) (serious criteria clinically significant/intervention required). The outcome of the vaccination failure, brain operation and shingles were not reported. It was unknown if the reporter considered the vaccination failure, brain operation and shingles to be related to Shingles vaccine. The company considered the vaccination failure, brain operation and shingles to be unrelated to Shingles vaccine. Additional Information: GSK Receipt Date: 03-MAR-2026 This case was reported by a patient via interactive digital media The patient was sorry they had listened to people talk about getting vaccinated. The patient had been vaccinated about seven years earlier, and they believed that. On 31 January 2026 it hit the patient that they had never known what was going on with them; the pain was truly unbearable, they said. The patient went to bed the next day. They could not move; it had taken over their central nervous system. All they could do was pray to God for help because they could not move. They began to cry, wondering what was happening because they did not know. The patient developed shingles before long they had blisters on the left side of their back that hurt terribly. When their aide came to help, the patient asked the aide to take a picture of the blisters. They sent the picture to their social media page and to family members. One friend told them they had shingles and needed to go to the doctor's office as soon as possible. The patient told the friend that they could not move and that it was hard to believe; they did not know whether a low immune system was causing their difficulties. They said that shingles made them think about life and that it worried them more than having had brain surgery. The patient said they had been praying to God for better days to come. The batch number was not provided and we and unable to contact the reporter. This case was considered as suspected vaccination failure as details regarding laboratory test confirming shingles were unknown at the time of reporting.; Sender's Comments: A case of Vaccination failure, Brain operation and Herpes zoster, an unknown time after receiving Shingles vaccine, in a 59-year-old patient. Based on the available information, a possible causality that the event was caused by the GSK product cannot be ascertained. Consent for further follow-up has not been received.