Received Mar 10, 2026
| Type | Name | Manufacturer | Dose | Lot | Route / Site |
|---|---|---|---|---|---|
| UNK | VACCINE NOT SPECIFIED (NO BRAND NAME) | UNKNOWN MANUFACTURER | UNK | — | — |
She had no response to pneumococcal vaccination (0/23); This Literature (Spontaneous) report has been received from the authors of a published article, titled as stated below, concerning a 34-year-old female patient, who had a childhood history of recurrent sinopulmonary infections and was referred to Immunology. She was diagnosed with granulomatosis with polyangiitis (GPA) at age 30 and started rituximab therapy at that age. One year after treatment initiation, she developed frequent pneumonias. and chronic sinusitis requiring multiple hospitalizations and surgery. Immunoglobulin testing revealed pan-hypogammaglobulinemia On an unknown date, the patient was vaccinated with Pneumococcal Vaccine, Polyvalent (23-valent) (PNEUMOVAX 23) as prophylaxis (dose, schedule, lot number, expiration date, route or site of administration were unknown). Also on an unknown date, it was discovered that she had no response to Pneumococcal Vaccine, Polyvalent (23-valent) (PNEUMOVAX 23) vaccination (vaccination failure). A copy of the published article is attached as further documentation of the patient's experience. Literature Report.
Granulomatosis with polyangiitis
Medical History/Concurrent Conditions: Bronchopulmonary infection; Chronic sinusitis; Immunoglobulins (revealed pan-hypogammaglobulinemia); Pneumonia