Report #2889053

Overview

Sex

Female

Age

Age unknown

State

MD

Recovered

Not recovered

Vaccinated

—

Onset

—

Days to onset

—

Hospital days

—

Symptoms (2)

Symptom narrative

Suspected vaccination failure; Developed shingles in eye; This serious case was reported by a consumer via call center representative and described the occurrence of vaccination failure in a 70-year-old female patient who received Herpes zoster (Shingrix) for prophylaxis. Co-suspect products included Herpes zoster (Shingrix) for prophylaxis. Previously administered products included Varicella zoster vaccine (received two doses in 2005, around twenty years ago and was around 50 years old). On an unknown date, the patient received the 2nd dose of Shingrix and the 1st dose of Shingrix. On an unknown date, more than 2 years after receiving Shingrix and Shingrix, the patient experienced vaccination failure (Verbatim: Suspected vaccination failure) (serious criteria GSK medically significant) and ophthalmic herpes zoster (Verbatim: Developed shingles in eye) (serious criteria GSK medically significant). The outcome of the vaccination failure was not reported and the outcome of the ophthalmic herpes zoster was not resolved. It was unknown if the reporter considered the vaccination failure and ophthalmic herpes zoster to be related to Shingrix and Shingrix. The company considered the vaccination failure and ophthalmic herpes zoster to be unrelated to Shingrix and Shingrix. Additional Information: GSK Receipt Date: 06-MAR-2026 The patient received both shots of Shingrix and she was around 60 to 61 years old. The patient had developed shingles in her eye in 2024, and had dealt with that for about 2 years, when she was around 68 years old. This case was considered as suspected vaccination failure as details regarding laboratory test confirming shingles were unknown at the time of reporting. The batch number was not provided and a request for this information has been made.; Sender's Comments: A case of Vaccination failure and Ophthalmic herpes zoster, more than 2 years after vaccination with the 2nd dose of Shingrix and the 1st dose of Shingrix, in a 70-year-old female patient. Based on the available information a possible causality that the events were caused by GSK vaccine product cannot be ascertained. Consent for further follow up has not been received