Received Mar 18, 2026
| Type | Name | Manufacturer | Dose | Lot | Route / Site |
|---|---|---|---|---|---|
| TYP | TYPHOID LIVE ORAL TY21A (VIVOTIF) | BERNA BIOTECH, LTD. | 2 | unknown | PO / MO |
The patient took second dose of Vivotif and thrown up; The patient took first dose of Vivotif and thrown up; Case reference number US-BN-2025-000350 is a spontaneous case initially received from pharmacist via Communication (reference number: USBAV25-0561) on 12-Mar-2025 and concerns 18-year-old, female patient. The patient had no medical history. The patient's concomitant medication details were not provided. On 10-Mar-2025, the patient took the first dose of Vivotif (batch number: unknown) orally, at unknown dose, for indication pre travel. On the same day, also reported as an hour after the patient took Vivotif, the patient thrown up. On 12-Mar-2025, two days after the first dose, the patient took second dose of Vivotif (batch number: unknown) orally, at unknown dose. On the same day, also reported as 30 minutes after the patient took Vivotif, the patient thrown up. At the time of the initial report, the patient did not recover from the event 'vomiting of medication' after the first and second dose. The reporter assessed event of 'vomiting of medication' as non-serious and related to Vivotif. No further information was provided.; Reporter's Comments: An 18-year-old female patient thrown up one hour after taking Vivotif orally, at unknown dose, for indication pre travel. Two days after the first dose, the patient took second dose of Vivotif orally, at unknown dose and 30 minutes after taking Vivotif the patient thrown up again. Vomiting is listed and expected according to CCDS v8 and USPI. The outcome was not resolved. The patient had no medical history while concomitant medication details were not provided. Causality is assessed as related due to plausible temporal relationship, known product safety profile, lack of alternative explanation and since contributory role of suspect product cannot be excluded. The case is non-serious.; Sender's Comments: An 18-year-old female patient thrown up one hour after taking Vivotif orally, at unknown dose, for indication pre travel. Two days after the first dose, the patient took second dose of Vivotif orally, at unknown dose and 30 minutes after taking Vivotif the patient thrown up again. Vomiting is listed and expected according to CCDS v8 and USPI. The outcome was not resolved. The patient had no medical history while concomitant medication details were not provided. Causality is assessed as related due to plausible temporal relationship, known product safety profile, lack of alternative explanation and since contributory role of suspect product cannot be excluded. The case is non-serious.
Comments: NONE