Received Mar 18, 2026
| Type | Name | Manufacturer | Dose | Lot | Route / Site |
|---|---|---|---|---|---|
| TYP | TYPHOID LIVE ORAL TY21A (VIVOTIF) | BERNA BIOTECH, LTD. | 2 | Unknown | PO / MO |
The patient picked up the Vivotif vaccine at the pharmacy, took one dose of Vivotif and then left the vaccine out at maximum temperature of 74 degrees Fahrenheit for 24 hours, and after that put the vaccine back in refrigerator and took second dose; The patient picked up the Vivotif vaccine at the pharmacy, took one dose of Vivotif and then left the vaccine out at maximum temperature of 74 degrees Fahrenheit for 24 hours, and after that put the vaccine back in refrigerator and took second dose; The patient picked up the Vivotif vaccine at the pharmacy, took one dose of Vivotif and then left the vaccine out at maximum temperature of 74 degrees Fahrenheit for 24 hours, and after that put the vaccine back in refrigerator and took second dose; Case reference number US-BN-2025-000856 is a spontaneous case initially received from a pharmacist via Communication (reference number: USBAV25-0887) on 22-Apr-2025 and concerns a female patient of unspecified age, reported as patient is a "little bit older". The patient's medical history and concomitant medication details were not provided. On an unspecified date, the patient took first dose of Vivotif (batch number: unknown), at an unknown dose, orally, for indication typhoid prophylaxis and then left the vaccine out at maximum temperature of 74 degrees Fahrenheit for 24 hours (explicitly coded as 'product storage error temperature too high' and 'product temperature excursion issue'), and after 24 hours the patient realized it should be in the refrigerator, put it back in the refrigerator and took second dose of Vivotif (batch number: unknown), at an unknown dose, orally (explicitly coded as 'product administration error'). At the time of initial report, it was unknown if the patient experienced any adverse event due to Vivotif vaccine. No further information was provided.; Reporter's Comments: This case concerns a female patient of unspecified age/age group. As reported on an unspecified date, the patient took first dose of Vivotif vaccine, for an indication of typhoid prophylaxis and then left the vaccine out at maximum temperature of 74 degrees Fahrenheit for 24 hours which is considered as 'product storage error temperature too high' and 'product temperature excursion issue'. After 24 hours the patient realized it should be in the refrigerator, put it back in the refrigerator and took second dose of Vivotif, which is considered as 'product administration error'. At the time of initial report, it was unknown if the patient experienced any adverse events due to Vivotif vaccine. Product temperature excursion issue, product storage error temperature too high and product administration error are considered as listed as per company convention. The patients' medical history and concomitant medication details were not provided. Product temperature excursion issue, product storage error temperature too high and product administration error are not related to the suspect vaccine, but to a human factor. This case is considered as non-serious.; Sender's Comments: This case concerns a female patient of unspecified age/age group. As reported on an unspecified date, the patient took first dose of Vivotif vaccine, for an indication of typhoid prophylaxis and then left the vaccine out at maximum temperature of 74 degrees Fahrenheit for 24 hours which is considered as 'product storage error temperature too high' and 'product temperature excursion issue'. After 24 hours the patient realized it should be in the refrigerator, put it back in the refrigerator and took second dose of Vivotif, which is considered as 'product administration error'. At the time of initial report, it was unknown if the patient experienced any adverse events due to Vivotif vaccine. Product temperature excursion issue, product storage error temperature too high and product administration error are considered as listed as per company convention. The patients' medical history and concomitant medication details were not provided. Product temperature excursion issue, product storage error temperature too high and product administration error are not related to the suspect vaccine, but to a human factor. This case is considered as non-serious.
Comments: None