Received Mar 20, 2026
| Type | Name | Manufacturer | Dose | Lot | Route / Site |
|---|---|---|---|---|---|
| TYP | TYPHOID LIVE ORAL TY21A (VIVOTIF) | BERNA BIOTECH, LTD. | 4 | Unknown | PO / MO |
The patient was late about 16 hours with fourth dose of Vivotif vaccine; The patient ate one half chocolate bar and fruit leather ten minutes prior to taking the fourth dose of Vivotif; Case reference number US-BN-2024-002087 is a spontaneous case initially received from nurse via Communications (reference number USBAV24-1459) on 24-Jun-2024 and concerns a female patient of unspecified age. The patient's medical history and concomitant medication details were not provided. On unspecified dates, the patient took three doses of Vivotif vaccine (batch number: unknown), at unknown dose, orally, for typhoid fever immunisation. On an unspecified date, unknown amount of time after the third dose, as reported, dose was late about 16 hours, patient took fourth dose of Vivotif (batch number: unknown), at unknown dose, orally. As reported, the patient ate one half chocolate bar and fruit leather ten minutes prior to taking the dose (explicitly coded as 'Product administration error' and 'Inappropriate schedule of vaccine administered'). At the time of the initial report, it was unknown if the patient experienced any adverse event due to Vivotif vaccine. Non-significant follow up was downloaded from VAERS on 09-May-2025 included new reference number Administrative update performed within the case: Worldwide Unique Case Identification Number (WWID) updated from US-20240624-915913 to US-BAVARIAN NORDIC A/S-US-BN-2024-002087, in accordance with ICH guidance on WWID formatting.; Reporter's Comments: A female patient of unspecified age took the fourth dose of Vivotif, and the dose was late about 16 hours. As reported, the patient ate one half chocolate bar and fruit leather ten minutes prior to taking the dose, which is considered as product administration error and inappropriate schedule of vaccine administered. It was unknown if the patient experienced any adverse event due to Vivotif vaccine. Inappropriate schedule of product administration and product administration error are considered as listed per company convention. The patient's medical history and concomitant medication were not provided. Inappropriate schedule of product administration and product administration error have been considered as not related to the suspect vaccine, but to a human factor. This case is considered as non-serious.; Sender's Comments: A female patient of unspecified age took the fourth dose of Vivotif, and the dose was late about 16 hours. As reported, the patient ate one half chocolate bar and fruit leather ten minutes prior to taking the dose, which is considered as product administration error and inappropriate schedule of vaccine administered. It was unknown if the patient experienced any adverse event due to Vivotif vaccine. Inappropriate schedule of product administration and product administration error are considered as listed per company convention. The patient's medical history and concomitant medication were not provided. Inappropriate schedule of product administration and product administration error have been considered as not related to the suspect vaccine, but to a human factor. This case is considered as non-serious. USBAV24-1459:
Comments: None