Received Mar 25, 2026
| Type | Name | Manufacturer | Dose | Lot | Route / Site |
|---|---|---|---|---|---|
| COVID19 | COVID19 (COVID19 (MODERNA MNEXSPIKE)) | MODERNA | UNK | — | IM |
significant swelling of my right thumb tendon/swelling of the whole thumb; trigger finger at the DIP joint; pain in the MCP joint; tendinopathy; Patient administered 1 milliliter dose; This spontaneous case was reported by a physician and describes the occurrence of PERIPHERAL SWELLING (significant swelling of my right thumb tendon/swelling of the whole thumb), TRIGGER FINGER (trigger finger at the DIP joint), ARTHRALGIA (pain in the MCP joint) and TENDON DISORDER (tendinopathy) in a 72-year-old male patient who received mRNA-1273.251 (Spikevax LP.8.1 PFS) for COVID-19 prophylaxis. The occurrence of additional non-serious events is detailed below. Co-suspect product included Pre-filled Syringe injection for COVID-19 prophylaxis. Previously administered products included for Product used for unknown indication: PFIZER BIONTECH COVID-19 VACCINE. Past adverse reactions to the above products included No adverse effect with PFIZER BIONTECH COVID-19 VACCINE. On 14-Mar-2026, the patient received dose of mRNA-1273.251 (Spikevax LP.8.1 PFS) (Intramuscular use) 1 milliliter. On an unknown date, the patient started Pre-filled Syringe (unknown route) at an unspecified dose. On 14-Mar-2026, after starting mRNA-1273.251 (Spikevax LP.8.1 PFS), the patient experienced OVERDOSE (Patient administered 1 milliliter dose). On 15-Mar-2026, the patient experienced PERIPHERAL SWELLING (significant swelling of my right thumb tendon/swelling of the whole thumb) (seriousness criterion medically significant), TRIGGER FINGER (trigger finger at the DIP joint) (seriousness criterion medically significant), ARTHRALGIA (pain in the MCP joint) (seriousness criterion medically significant) and TENDON DISORDER (tendinopathy) (seriousness criterion medically significant). At the time of the report, PERIPHERAL SWELLING (significant swelling of my right thumb tendon/swelling of the whole thumb), TRIGGER FINGER (trigger finger at the DIP joint), ARTHRALGIA (pain in the MCP joint) and TENDON DISORDER (tendinopathy) had not resolved and OVERDOSE (Patient administered 1 milliliter dose) outcome was unknown. For mRNA-1273.251 (Spikevax LP.8.1 PFS) (Intramuscular use), the reporter considered PERIPHERAL SWELLING (significant swelling of my right thumb tendon/swelling of the whole thumb), TRIGGER FINGER (trigger finger at the DIP joint), ARTHRALGIA (pain in the MCP joint) and TENDON DISORDER (tendinopathy) to be related. No further causality assessment was provided for OVERDOSE (Patient administered 1 milliliter dose). For Pre-filled Syringe, the reporter did not provide any causality assessments. No concomitant medication was reported., Patient subsequently used the Pfizer vaccine however this last week patient again selected the Moderna covid vaccine It was noticing tendinopathy was not recognized as a side effect of mRNA vaccine however this was definitely a consequence of the vaccination and thought it should be notified. The patient did not experience any additional symptoms/events. There were no lab data/results available. No treatment information was reported. This case was linked to MOD-2026-794527 (Patient Link).; Reporter's Comments: The benefit-risk relationship of product is not affected by this report.