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Report #2891048

Received Mar 27, 2026

A note on interpretation. VAERS reports are unverified and may be incomplete or coincidental. A report does not establish that a vaccine caused an event, and counts should not be used to calculate incidence or infer causation. Full disclaimer

Overview

Sex
Female
Age
37 yrs
State
OH
Recovered
Not recovered
Vaccinated
Mar 19, 2026
Onset
Mar 19, 2026
Days to onset
0
Hospital days
—

Vaccines (1)

TypeNameManufacturerDoseLotRoute / Site
SMALLMNKSMALLPOX + MONKEYPOX (JYNNEOS)BAVARIAN NORDIC1484113SC / LA

Symptoms (3)

HeadacheInjection site erythemaInjection site induration

Symptom narrative

Member experienced an adverse event following immunization (AEFI) after her 1st dose of JYNNEOS. On 19 Mar 2026, she received JYNNEOS 0.5 mL subcutaneously in left arm for readiness for pre-event smallpox protection. She experienced redness and induration at injection site that measured up to 6 cm wide, persisting thru today (8 days after vaccination). She reported exacerbation of headaches over the week after vaccination as well. This AEFI likely represents a robust immune response, experienced both locally and systemically.

Current illness

Migraine disorder

Medical history

Migraine disorder

Other medications

ondansetron 4 mg oral tablet, disintegrating, PRN, amitriptyline 50 mg oral tablet; 1 tab nightly for headache prevention,

Allergies

NKDA