Received Apr 9, 2026
| Type | Name | Manufacturer | Dose | Lot | Route / Site |
|---|---|---|---|---|---|
| VARZOS | ZOSTER (SHINGRIX) | GLAXOSMITHKLINE BIOLOGICALS | UNK | 4A4BM | — |
| VARZOS | ZOSTER (SHINGRIX) | GLAXOSMITHKLINE BIOLOGICALS | UNK | 4A4BM | — |
a patient received only half a dose; they went to plunge, the liquid leaked and a patient received only half dose; quality issue in the Shigrix prefilled syringe, a patient didn't receive a full dose of the Shingrix vaccine; This non-serious case was reported by a non-health professional via call center representative and described the occurrence of underdose in a patient who received Herpes zoster (Shingrix) (batch number 4A4BM, expiry date 18-MAR-2027) for prophylaxis. This case was associated with a product complaint. Co-suspect products included Herpes zoster (Shingrix) (batch number 4A4BM, expiry date 18-MAR-2027) for prophylaxis. On an unknown date, the patient received Shingrix .5 ml and Shingrix. On an unknown date, an unknown time after receiving Shingrix and Shingrix, the patient experienced underdose (Verbatim: a patient received only half a dose), product leakage (Verbatim: they went to plunge, the liquid leaked and a patient received only half dose) and pharmaceutical product complaint (Verbatim: quality issue in the Shigrix prefilled syringe, a patient didn't receive a full dose of the Shingrix vaccine). The outcome of the underdose, product leakage and pharmaceutical product complaint were not applicable. This report is made by GSK without prejudice and does not imply any admission or liability for the incident or its consequences. Additional Information: GSK Receipt Date: 30-MAR-2026 The reporter stated that he had the suspected Prefilled syringe (PFS) in his custody and they were available to be returned to the company for investigation. The reporter stated that facility health care professional (HCP) was giving patient the Shingrix PFS vaccine and while administering, the vaccine leaked and squirted out of the back through the plunger. HCP called to inform that when using a Shingrix PFS and they went to plunge, the liquid leaked and a patient received only half a dose. Reporter added that the physician in charge gave the instruction on that same visit to administer another dose to the patient, and that the same quality issue occurred with the syringe. The reporter mentioned that between the two half doses they believe the patient had received a full dose. The batch number was not provided, and we are unable to contact the reporter.