Received May 20, 2026
| Type | Name | Manufacturer | Dose | Lot | Route / Site |
|---|---|---|---|---|---|
| VARZOS | ZOSTER (SHINGRIX) | GLAXOSMITHKLINE BIOLOGICALS | UNK | UNK | — |
Suspected vaccination failure; the most dangerous type you can get, internal shingles; It attacked its esophagus and diaphragm; It attacked its esophagus and diaphragm; He lost 11 lbs in less than a week.; he had issues swallowing; This serious case was reported by a consumer via interactive digital media and described the occurrence of vaccination failure in a male patient who received Herpes zoster (Shingrix) for prophylaxis. On an unknown date, the patient received Shingrix. On an unknown date, 6 months after receiving Shingrix, the patient experienced vaccination failure (Verbatim: Suspected vaccination failure) (serious criteria GSK medically significant), zoster sine herpete (Verbatim: the most dangerous type you can get, internal shingles), esophageal disorder (Verbatim: It attacked its esophagus and diaphragm), diaphragmatic disorder (Verbatim: It attacked its esophagus and diaphragm), weight loss (Verbatim: He lost 11 lbs in less than a week.) and swallowing difficult (Verbatim: he had issues swallowing). The outcome of the vaccination failure, zoster sine herpete, esophageal disorder, diaphragmatic disorder, weight loss and swallowing difficult were not reported. It was unknown if the reporter considered the vaccination failure, zoster sine herpete, esophageal disorder, diaphragmatic disorder, weight loss and swallowing difficult to be related to Shingrix. The company considered the vaccination failure to be unrelated to Shingrix. It was unknown if the company considered the zoster sine herpete, esophageal disorder, diaphragmatic disorder, weight loss and swallowing difficult to be related to Shingrix. Additional Information: GSK Receipt date: 13-MAY-2026 This case was reported by a patient via interactive digital media. The patient took the shingles vaccine to prevent shingles. The patient got the shingles 6 months after getting the vaccine. The patient was lucky that there was no involvement of the liver, kidneys, intestinal tract, or brain. The patient had only one tiny surface on his skin everything else was internal. The batch number was not provided, and we are unable to contact the reporter. This case was considered as suspected vaccination failure as details regarding completion of primary vaccination schedule, time to onset for shingles and laboratory confirmation regarding shingles were unknown at the time of reporting.; Sender's Comments: A case of Vaccination failure, 6 months after receiving Shingrix, in a patient. Case lacks further information on exact time to onset, medical history, concurrent conditions, completion of primary vaccination schedule and laboratory confirmation. Based on the available information, a possible causality that the event was caused by the GSK product cannot be ascertained. Consent for further follow-up has not been received.