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Report #2899061

Received Jun 4, 2026

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A note on interpretation. VAERS reports are unverified and may be incomplete or coincidental. A report does not establish that a vaccine caused an event, and counts should not be used to calculate incidence or infer causation. Full disclaimer

Overview

Sex
Female
Age
57 yrs
State
NC
Recovered
Not recovered
Vaccinated
Mar 12, 2021
Onset
Jan 16, 2022
Days to onset
310
Hospital days
—

Vaccines (2)

TypeNameManufacturerDoseLotRoute / Site
COVID19COVID19 (COVID19 (MODERNA))MODERNA2038A21ASYR / AR
COVID19COVID19 (COVID19 (MODERNA))MODERNA2002C21ASYR / AR

Symptoms (19)

Biopsy bone marrow abnormalChest discomfortDyspnoeaElectromyogram abnormalElectrophoresis proteinFlow cytometryFluorescent in situ hybridisationGenital hypoaesthesiaHypergammaglobulinaemia benign monoclonalHypoaesthesiaHypoaesthesia oralImmunoglobulins increasedLight chain analysis abnormalLight chain analysis increasedMonoclonal immunoglobulin presentPainPlasmacytomaProtein total normalSmall fibre neuropathy

Symptom narrative

Following receipt of Moderna COVID-19 vaccine Dose 2 on April 26, 2021, I developed progressive bilateral neuropathy beginning January 2022 ? 8 months post-vaccination. Symptoms include chronic burning pain, numbness and tingling in both legs, feet, hands, fingers, lips, and perineal area. I presented to the ER on April 1, 2022 with chest pressure and difficulty breathing. I was subsequently diagnosed with Small Fiber Neuropathy and Monoclonal Gammopathy of Undetermined Significance ? IgG Kappa. EMG studies in April 2022 confirmed bilateral absent sural and peroneal sensory responses. October 2025 EMG confirmed progression with new upper extrem

Current illness

No

Medical history

Pre-diabetic and High blood pressure

Allergies

Lisinopril

Lab data

superficial peroneal sensory responses ? abnormal. August 2022 ? SPEP: M-spike 0.17 g/dL ? MGUS detected. December 2022 ? Bone marrow biopsy: 3% plasma cells kappa predominant. January 2023 ? FISH panel: incomplete due to insufficient CD138+ cells. October 2025 ? EMG: progression confirmed ? new upper extremity sensory involvement. April 2026 ? SPEP: M-spike 0.31 g/dL, Gamma 2.08 g/dL, Total Protein 8.1 g/dL ? all elevated. April 2026 ? Free Light Chain Kappa: 5.54 mg/dL ? nearly 3x normal. Kappa/Lambda ratio approximately 3.6 ? abnormal. June 2026 ? Bone marrow biopsy SP26-026203: kappa-restricted plasma cells 2-3%, CD56 positive, Cyclin D1 positive ? confirmed plasma cell neoplasm. June 2026 ? Flow cytometry FC26-3014: 0.19% plasma cells ? flow cytometry underestimated burden per pathologist note.