Received Jun 10, 2026
| Type | Name | Manufacturer | Dose | Lot | Route / Site |
|---|---|---|---|---|---|
| HEPAB | HEP A + HEP B (TWINRIX) | GLAXOSMITHKLINE BIOLOGICALS | UNK | — | LA |
itching on hands and feet; blisters on feet, toes and hands; This non-serious case was reported by a consumer via call center representative and described the occurrence of pruritus in a 60-year-old male patient who received HAB (Twinrix) suspension for injection in pre-filled syringe for prophylaxis. Concurrent medical conditions included cough (the time of vaccination had an ongoing, lingering bad cough that patient had for weeks). On 02-APR-2026, the patient received Twinrix (left arm). In APR-2026, between 1 and 2 weeks after receiving Twinrix, the patient experienced pruritus (Verbatim: itching on hands and feet) and blister (Verbatim: blisters on feet, toes and hands). The patient was treated with prednisone and steroids. The outcome of the pruritus and blister were resolved. It was unknown if the reporter considered the pruritus and blister to be related to Twinrix and Twinrix Pre-Filled Syringe Device. This report is made by GSK without prejudice and does not imply any admission or liability for the incident or its consequences. Additional Information: GSK Receipt Date: 08-JUN-2026 The patient self-reported this case for herself. The patient was treated by a dermatologist with a high dose taper of Prednisone 80 mg and steroid creams. The patient stated that a biopsy was taken and had the results that he wanted to share with the GlaxoSmithKline safety team. The patient stated that had an appointment on the day of reporting with a physician concerning this adverse event. The patient stated that after taking the Prednisone and applying the steroid creams, the blisters and itching had resolved completely. The patient had not reported this complaint previously to the company, either personally or through anyone on his behalf. The batch number was not provided upon follow up with the reporter.
Cough (the time of vaccination had an ongoing, lingering bad cough that patient had for weeks)
Test Name: biopsy; Result Unstructured Data: (Test Result:unknown,Unit:unknown,Normal Low:,Normal High:); Test Name: COVID; Result Unstructured Data: (Test Result:negative,Unit:unknown,Normal Low:,Normal High:)