Received Jun 19, 2026
| Type | Name | Manufacturer | Dose | Lot | Route / Site |
|---|---|---|---|---|---|
| VARZOS | ZOSTER (SHINGRIX) | GLAXOSMITHKLINE BIOLOGICALS | 2 | UNK | — |
| VARZOS | ZOSTER (SHINGRIX) | GLAXOSMITHKLINE BIOLOGICALS | 1 | UNK | — |
suspected vaccination failure/Lack of drug effect; had shingles more than 7 times; This serious case was reported by a consumer via interactive digital media and described the occurrence of vaccination failure in a 70-year-old female patient who received Herpes zoster (Shingrix) for prophylaxis. The patient's past medical history included shingles (at the age of 12) and shingles (once in the early 1990s). Previously administered products included live shingles vaccine. On an unknown date, the patient received the 2nd dose of Shingrix. On an unknown date, an unknown time after receiving Shingrix, the patient experienced vaccination failure (Verbatim: suspected vaccination failure/Lack of drug effect) (serious criteria GSK medically significant) and shingles (Verbatim: had shingles more than 7 times). The outcome of the vaccination failure was unknown and the outcome of the shingles was not reported. It was unknown if the reporter considered the vaccination failure and shingles to be related to Shingrix. The company considered the vaccination failure to be unrelated to Shingrix. Additional Information: GSK Receipt Date: 13-JUN-2026 This case was reported by a patient via interactive digital media. The patient self-reported this case for herself. The patient hoped it had worked for others, but not for them. The patient stated that since receiving the live shingles vaccine and two doses of the Shingrix vaccine, the patient had shingles more than seven times. The batch number was not provided and unable to contact the reporter. This case was considered as suspected vaccination failure as details regarding time to onset and laboratory test confirming shingles were unknown at the time of reporting.; Sender's Comments: A case of Vaccination failure, unknown time after receiving 2nd dose of Shingrix in a 70-year-old female patient. Case lacks further information on time to onset, medical history, concurrent conditions and laboratory confirmation. Based on the available information a possible causality that the event was caused by the GSK product cannot be ascertained. Consent for further follow-up has not been received.
Medical History/Concurrent Conditions: Shingles (once in the early 1990s); Shingles (at the age of 12)